Adenike A Akinsemolu1,2*, Felix A Akinyosoye1 and Daniel J Arotupin DJ1
1Department of Microbiology, Federal University of Technology, Akure, Nigeria
2The Green Institute, Ondo, Nigeria
*Corresponding Author: Adenike A Akinsemolu, Department of Microbiology, Federal University of Technology, Akure, Nigeria.
Received: April 25, 2018; Published: May 22, 2018
Citation: S Adenike A Akinsemolu.,et al. "The Ecotoxicological Dynamics of the Coastal Marine Ecosystem of Oil-Producing Areas in Ilaje Ondo State, Nigeria". Acta Scientific Microbiology 1.6 (2018).
Oral diseases major responsible of dental caries that continue to be major health problem through the world. The oral diseases treatment options and products required the global need for alternative prevention method. Medicinal plants extracts could serve as an important natural alternative to prevent microbial growth in oral infection diseases. This study was undertaken to determine the in vitro anticariogenic activities of 19 medicinal plants leaves and fruits against dental pathogenic bacteria. In vitro antibacterial potential of the ethyl acetate, hexane, methanol and distilled water extracts was evaluated by using four cariogenic bacteria, Lactobacillus acidophilus (LA); Lactobacillus casei(LC); Streptococcus mutans (SM) and Staphylococcus aureus (SA). The antibacterial activity study by agar well diffusion method and MIC. The good MIC values showed those all selected plants study for Phytochemical evaluation and TLC – bioautography. The ethyl acetate extract of plant leaves showed the more potent anticariogenic activities against oral pathogen. The fruit extract is more powerful compared to leaves extract as far as growth inhibition in cariogenic bacteria of selected ethanomedicinal plants. High degree of growth inhibition (19 - 25 mm) was found when plant extracts of Coroupita guia- nensis (Fruit) tested against Lactobacillus casei by various extracts of three plants which is more than that of the standard antibiotic erythromycin (19 mm). The MIC of methanol extract of Coroupita guianensis (Fruit) against Lactobacillus casei was 0.16 mg/ml. The based on the MIC data selected plants for preliminary phytochemical analysis revealed the presence of alkaloids in the all plants extracts. The methanol extract of Coroupita guianensis L. (Fruit) in present the Cardiac glycoside, steroids, Terpenoids and phenolic compound. The resulted chromatogram was used for bioautography against Lactobacillus casei. This study revealed that Coroupita guianensis is natural alternative to prevent the oral disease.
Keywords: Ethano-Medicinal Plants; Oral Disease; Cariogenic Bacteria; Bioautography
Copyright: © Kalpesh Ishnava., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.