Acta Scientific Microbiology

Conceptual PaperVolume 1 Issue 4

Toxoplasma gondii : A Journey into the Brain

Dalia S Ashour*

Medical Parasitology Department, Faculty of Medicine, Tanta University, Egypt

*Corresponding Author: Dalia S Ashour, Medical Parasitology Department, Faculty of Medicine, Tanta University, Egypt.

Received: February 03, 2018; Published: March 26, 2018

DOI: 10.31080/ASMI.2018.01.0042

Citation: Dalia S Ashour. “ Toxoplasma gondii : A Journey into the Brain”. Acta Scientific Microbiology 1.4 (2018).

Bibliography

  1. Hill DE., et al . “Biology and epidemiology of Toxoplasma gondii in man and animals”. Animal Health Research Reviews 6.1 (2005): 41-61.
  2. Robert-Gangneux F and Dardé ML. “Epidemiology of and di - agnostic strategies for toxoplasmosis”. Clinical Microbiology Reviews 25.2 (2012): 264-296.
  3. Dubey J. “Toxoplasmosis of Animals and Humans”. Second Edition [Internet]. Parasites and Vectors. CRC Press (2009).
  4. Barragan A and Sibley LD. “Migration of Toxoplasma gon- dii across biological barriers”. Trends in Microbiology 11.9 (2003): 426-430.
  5. Courret N., et al . “CD11c- and CD11b-expressing mouse leu - kocytes transport single Toxoplasma gondii tachyzoites to the brain”. Blood 107.1 (2006): 309-316.
  6. Pavesio CE and Lightman S. “Toxoplasma gondii and ocular toxoplasmosis: pathogenesis”. British Journal of Ophthal- mology 80.12 (1996): 1099-1107.
  7. Montoya JG and Remington JS. “Management of Toxoplasma gondii infection during pregnancy”. Clinical Infectious Dis- eases 47.4 (2008): 554-566.
  8. Feustel SM., et al . “Toxoplasma gondii and the blood-brain barrier”. Virulence 3.2 (2012): 182-192.
  9. Verma S., et al . “West Nile virus infection modulates human brain microvascular endothelial cells tight junction proteins and cell adhesion molecules: Transmigration across the in vitro blood-brain barrier”. Virology 385.2 (2009): 425-433.
  10. Chai Q., et al . “Enhancement of blood-brain barrier perme - ability and reduction of tight junction protein expression are modulated by chemokines/cytokines induced by rabies virus infection”. Journal of Virology 88.9 (2014): 4698-4710.
  11. Dobrowolski JM and Sibley LD. “Toxoplasma Invasion of Mammalian Cells Is Powered by the Actin Cytoskeleton of the Parasite”. Cell 84.6 (1996): 933-939.
  12. Barragan A and Sibley LD. “Transepithelial migration of Toxo- plasma gondii is linked to parasite motility and virulence”. Journal of Experimental Medicine 195.12 (2002): 1625-1633.
  13. Tardieux I and MeÂnard R. “Migration of Apicomplexa across biological barriers: The Toxoplasma and Plasmodium rides”. Traffic 9.5 (2008): 627-635.
  14. Gregg B., et al . “Replication and distribution of Toxoplasma gondii in the small intestine after oral infection with tissue cysts”. Infection and Immunity 81.5 (2013): 1635-1643.
  15. Konradt C., et al . “Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system”. Nature Microbiology 1 (2016): 16001.
  16. Conley FK and Jenkins KA. “Immunohistological study of the anatomic relationship of Toxoplasma antigens to the inflammatory response in the brains of mice chronically in - fected with Toxoplasma gondii”. Infection and Immunity 31.3 (1981): 1184-1192.
  17. Lambert H., et al . “Induction of dendritic cell migration upon Toxoplasma gondii infection potentiates parasite dissemina - tion”. Cellular Microbiology 8.10 (2006): 1611-1623.
  18. Lachenmaier SM., et al . “Intracellular transport of Toxoplas- ma gondii through the blood-brain barrier”. Journal of Neuro- immunology 232.1-2 (2011): 119-130.
  19. Carruthers VB., et al . “Secretion of micronemal proteins is associated with Toxoplasma invasion of host cells”. Cellular Microbiology 1.3 (1999): 225-235.
  20. Barragan A., et al . “Transepithelial migration of Toxoplasma gondii involves an interaction of intercellular adhesion mol- ecule 1 (ICAM-1) with the parasite adhesin MIC2”. Cellular Microbiology 7.4 (2005): 561-568.
  21. Dowse T and Soldati D. “Host cell invasion by the apicom- plexans: the significance of microneme protein proteolysis”. Current Opinion in Microbiology 7.4 (2004): 388-396.
  22. Unno A., et al . “Up-regulation of hyaluronan receptors in Toxoplasma gondii-infected monocytic cells”. Biochemical and Biophysical Research Communications 391.1 (2010): 477-480.
  23. Mendez OA and Koshy AA. “Toxoplasma gondii: Entry, asso - ciation, and physiological influence on the central nervous system”. PLoS Pathogens 13.7 (2017): e1006351.

Copyright: © 2018 Dalia S Ashour. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days

Indexed In






News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is April 30th, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US