Acta Scientific Dental Sciences (ASDS)(ISSN: 2581-4893)

Review Article Volume 7 Issue 12

Unveiling the Power of Local Drug Delivery in Treating Chronic Periodontitis

Aishwarya Dham MDS1*, Veenadevi Thonthula BDS2, Krishnapriya Edayilliam BDS3 and Hridya Jayaprakash MDS4

1Periodontist, Senior Lecturer, Department of Periodontology, Hazaribagh College of Dental Sciences and Hospital, Demotand, Hazaribagh, India
2General Dentist, Edmonton, Alberta T6X1Y9, Canada
33Former student of KVG Dental College, Kurinjibagh, Sullia, D.K, India
4Periodontist, Clove Dental, Sholinganallur, Chennai, Tamil Nadu, India

*Corresponding Author: Aishwarya Dham, Periodontist, Senior Lecturer, Department of Periodontology, Hazaribagh College of Dental Sciences and Hospital, Demotand, Hazaribagh, India.

Received: October 19, 2023; Published: November 28, 2023

Abstract

The concept of local medication delivery in periodontics pertains to the precise administration of medicinal substances directly into the periodontal pockets, which are the interdental areas where periodontal disease develops. The aforementioned drug delivery methods, including as gels, chips, microspheres, and membranes, have been specifically developed to address bacterial infection and inflammation localized to the affected area, with the aim of reducing any adverse effects on the entire system. The implementation of antimicrobial agents directly into the periodontal pockets using local drug delivery mechanisms ensures a continuous and controlled release of medication. This approach effectively manages the proliferation of pathogenic bacteria and facilitates the process of tissue healing. This method is frequently employed in conjunction with scaling and root planing, hence augmenting the overall efficacy of periodontal interventions. Dental professionals employ a meticulous approach in the selection and customization of delivery systems, taking into account the unique state of each patient. This practice significantly enhances the effectiveness of periodontal disease management, leading to improved outcomes.

Keywords:Periodontitis; Local Drug Delivery; Pockets

References

  1. Gasner NS and Schure RS. “Periodontal Disease”. In: StatPearls. Treasure Island (FL): StatPearls Publishing (2023).
  2. Tariq M., et al. “Treatment modalities and evaluation models for periodontitis”. International Journal of Pharmaceutical Investigation 3 (2012): 106-122.
  3. Puri K and Puri N. “Local drug delivery agents as adjuncts to endodontic and periodontal therapy”. Journal of Medicine and Life 4 (2013): 414-419. 
  4. Drisko CH. “Nonsurgical periodontal therapy”. Periodontology 2000 25 (2001): 77-88.
  5. Barca E., et al. “Adjunctive use of antibiotics in periodontal therapy”. Journal of Istanbul University Faculty of Dentistry 3 (2015): 55-62.
  6. Li J., et al. “Antimicrobial Activity and Resistance: Influencing Factors”. Frontiers in Pharmacology 8 (2017): 364.
  7. Panwar M and Gupta SH. “Local Drug Delivery with Tetracycline Fiber: An Alternative to Surgical Periodontal Therapy”. Medical Journal Armed Forces India 3 (2009): 244-246.
  8. Leekha S., et al. “General principles of antimicrobial therapy”. Mayo Clinic Proceedings 2 (2011): 156-167.
  9. Sholapurkar A., et al. “Professionally Delivered Local Antimicrobials in the Treatment of Patients with Periodontitis-A Narrative Review”. Dentistry Journal (Basel) 1 (2020): 2.
  10. Rosa CDDRD., et al. “Use of chlorhexidine chip after scaling and root planning on periodontal disease: A systematic review and meta-analysis”. The Saudi Dental Journal 1 (2021): 1-10.
  11. Calasans-Maia MD., et al. “Microspheres of alginate encapsulated minocycline-loaded nanocrystalline carbonated hydroxyapatite: therapeutic potential and effects on bone regeneration”. International Journal of Nanomedicine 14 (2019): 4559-4571.
  12. Deo V., et al. “Therapeutic Efficacy of Subgingivally Delivered Doxycycline Hyclate as an Adjunct to Non-surgical Treatment of Chronic Periodontitis”. Journal of Dental and Maxillofacial Research 1 (2011): e3.
  13. Issac AV., et al. “Management of Chronic Periodontitis Using Subgingival Irrigation of Ozonized Water: A Clinical and Microbiological Study”. Journal of Clinical and Diagnostic Research 8 (2015): ZC29-33.
  14. Amato M., et al. “Local Delivery and Controlled Release Drugs Systems: A New Approach for the Clinical Treatment of Periodontitis Therapy”. Pharmaceutics4 (2023): 1312.
  15. Wen H., et al. “Drug Delivery Approaches in Addressing Clinical Pharmacology-Related Issues: Opportunities and Challenges”. AAPS Journal6 (2013): 1327-1340.
  16. Sambunjak D., et al. “WITHDRAWN: Flossing for the management of periodontal diseases and dental caries in adults”. Cochrane Database of Systematic Reviews 4 (2019): CD008829.

Citation

Citation: Aishwarya Dham., et al. “Unveiling the Power of Local Drug Delivery in Treating Chronic Periodontitis".Acta Scientific Dental Sciences 7.12 (2023): 47-50.

Copyright

Copyright: © 2023 Aishwarya Dham., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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Impact Factor1.278

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