M Bouaamri*, C Moujoud and S Haitami
Department of Oral Surgery and Oral Medicine, Dental Consultation and Treatment Center, Ibn Rochd University Hospital Center, Faculty of Dental Medicine, Hassan II University, Casablanca, Morocco
*Corresponding Author: M Bouaamri, Department of Oral Surgery and Oral Medicine, Dental Consultation and Treatment Center, Ibn Rochd University Hospital Center, Faculty of Dental Medicine, Hassan II University, Casablanca, Morocco.
Received: December 17, 2025; Published: December 29, 2025
Background:Irritated fibroma is one of the most common benign reactive lesions of the oral cavity, typically affecting the buccal mucosa, tongue, or lips. Palatal involvement, however, is uncommon. When presenting with rapid growth, ulceration, and a reddish pedunculated appearance, such lesions may clinically mimic malignancy, raising significant diagnostic concern.
Case Presentation: We report the case of a 24-year-old female who presented with a painless, reddish, pedunculated mass arising from the central palate, evolving over two weeks. The lesion showed a rapid increase in size during three weeks of evolution. Clinical examination revealed a nodular mass measuring approximately 3 × 2.5 × 1.3 cm, with a firm consistency and an ulcerated surface. Due to its alarming growth rate and clinical features, a malignant tumor was strongly suspected. Complete surgical excision was performed.
Histopathological analysis revealed ulcerated squamous mucosa overlying a proliferation of spindle-shaped fibroblastic cells arranged in interlacing bundles within a collagen-rich stroma. No evidence of atypia, necrosis, or malignancy was identified. The final diagnosis was ulcerated irritated fibroma. The postoperative course was uneventful, and no recurrence was noted during the 8-month follow-up.
Conclusion: This case emphasizes an unusual palatal localization of irritated fibroma with features mimicking malignancy. It highlights the critical role of histopathological evaluation in distinguishing benign reactive lesions from oral malignancies, and underlines that rapid clinical growth is not invariably a sign of malignancy.
Keywords: Irritated Fibroma; Palate; Oral Cavity; Benign Lesion; Differential Diagnosis; Case report
Citation: M Bouaamri., et al. “Rapidly Growing Palatal Irritated Fibroma Mimicking Oral Malignancy: A Case Report".Acta Scientific Dental Sciences 10.1 (2026): 34-38.
Copyright: © 2026 M Bouaamri., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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