Viswanath Gurumurthy¹, Pradeep C Dathan², Chandrasekharan Nair K³*, Vishak M Kumar⁴ and Janaki Krishna J⁴

¹Associate Professor, Department of Dental Technology, College of Applied Medical Sciences, King Khalid University, KSA
²Professor and Head of the Department of Prosthodontics, Sri Sankara Dental College, Akathumuri, Thiruvananthapuram, Kerala, India
³Professor Emeritus, Department of Prosthodontics, Sri Sankara Dental College, Akathumuri, Thiruvananthapuram, Kerala, India
⁴PG Student, Department of Prosthodontics, Sri Sankara Dental College, Akathumuri, Trivandrum, Kerala, India

*Corresponding Author: K Chandrasekharan Nair, Professor Emeritus, Department of Prosthodontics, Sri Sankara Dental College, Akathumuri, Thiruvananthapuram, Kerala, India.

Received: February 24, 2025; Published: March 05, 2025

Abstract

Obstructive sleep apnea has a high prevalence, amongst the adult world population especially in the middle and old aged individuals. It has become a major public health concern because it makes the society morbid and affects the working potential of the adults. It has attracted the attention of the research workers and identified the associate risk factors that spans from snoring to obesity. The treatment involves life style modifications, wearing of oral appliances, surgeries and in select cases pharmacologic agents. Early detection of the disease avoids complications mainly related to obesity, diabetes and cardiac problems.

Keywords: Sleep Apnea; Obstructive Sleep Apnea; Sleep Apnea Syndrome; Lifestyle Changes; Obesity; Snoring; Polysomnography; Day Time Sleepiness; Burden of Disease

References

1. Suri TM., et al. “Systematic review and meta-analysis of the prevalence of obstructive sleep apnea in Indian adults”. Sleep Medicine Reviews 71 (2023).
2. Lyons MM., et al. “Global burden of sleep-disordered breathing and its implications”. Respirology 25 (2020): 690-702.
3. Dempsey JA., et al. “Pathophysiology of sleep apnea”. Physiological Reviews 90 (2008): 47-112.
4. Lim DC and Pack AI. “Obstructive Sleep Apnea: Update and Future”. Annual Review of Medicine 68 (2016): 99-112.
5. Glicksman A., et al. “Body Fat Distribution Ratios and Obstructive Sleep Apnea Severity in Youth with Obesity”. Journal of Clinical Sleep Medicine 4 (2017): 545-550.
6. Jehan S., et al. “Obstructive Sleep Apnea and Obesity: Implications for Public Health”. Sleep Medicine Disorder4 (2017): 00019.
7. Meyer JB and Knudson RC. “The sleep apnea syndrome Part 1: Diagnosis”. Journal of Prosthetic Dentistry 62 (1989): 675-679.
8. American Academy of Sleep Medicine. International classification of sleep disorders, 3^rd Darien (Il): American Academy of Sleep Medicine (2014).
9. Asthma and Lung UK. “Epworth Sleepiness Scale.
10. Bibbins-Domingo K., et al. “Screening for obstructive sleep apnea in adults: US Preventive Services Task Force recommendation statement”. JAMA 317 (2017): 407-414.
11. Peppard PE., et al. “Longitudinal study of moderate weight change and sleep-disordered breathing”. JAMA 23 (2000): 3015-3021.
12. Aboussouan LS., et al. “Treatment for obstructive sleep apnea: CPAP and beyond”. Cleveland Clinic Journal of Medicine 90 (2023): 755-765.
13. Buchwald H., et al. “Bariatric surgery: a systematic review and meta-analysis [published correction appears”. JAMA14 (2005): 1728.
14. Nastałek P., et al. “Impact of bariatric surgery on obstructive sleep apnea severity and continuous positive airway pressure therapy compliance-prospective observational study”. Scientific Reports 1 (2021): 5003.
15. Peromaa-Haavisto P., et al. “Obstructive sleepapnea: the effect of bariatric surgery after 12 months. A prospective multicenter trial”. Sleep Medicine 35 (2017): 85-90.
16. Bibbins-Domingo K., et al. “Screening for obstructive sleep apnea in adults: US Preventive Services Task Force recommendation statement”. JAMA 317 (2017): 407-414.
17. https://www.sleepfoundation.org/sleeping-positions/side-sleep
18. Kobayashi Y., et al. “The effect of an anterior bite plane on sleep apnea in a bruxist”. Journal of Dental Research 63 (1984): 323.
19. Simou E., et al. “Alcohol and the risk of sleep apnoea: a systematic review and meta-analysis”. Sleep Medicine 42 (2018): 38-46.
20. Kolla BP., et al. “The impact of alcohol on breathing parameters during sleep: a systematic review and meta-analysis”. Sleep Medicine Reviews 42 (2018): 59-67.
21. Burgos-Sanchez C., et al. “Impact of alcohol consumption on snoring and sleep apnea: a systematic review and meta-analysis”. Otolaryngology-Head and Neck Surgery 6 (2020): 1078-1086.
22. Iftikhar IH., et al. “Effects of exercise training on sleep apnea: a meta-analysis”. Lung1 (2014): 175-184.
23. Flávio Maciel Dias de Andrade. “Rodrigo Pinto Pedrosa, The role of physical exercise in obstructive sleep apnea”. The Brazilian Journal of Pulmonology 6 (2016): 457-464.
24. Meyer JB and Knudson RC. “Sleep apnea syndrome Part 2: treatment”. Journal of Prosthetic Dentistry 63 (1990): 320-324.
25. Laratta CR., et al. “Diagnosis and treatment of obstructive sleep apnea in adults”. CMAJ 189 (2017): E1481-488.
26. Salord N., et al. “A Randomized controlled trial of continuous positive airway pressure on glucose tolerance in obese patients with obstructive sleep apnea”. Sleep 39 (2016): 35-41.
27. Wang ML., et al. “Cognitive effects of treating obstructive sleep apnea: a meta-analysis of randomized controlled trials”. Journal of Alzheimer's Disease 3 (2020): 705-715.
28. Sleeper G., et al. “Comparison of expiratory pressures generated by four different EPAP devices in a laboratory bench setting”. Sleep Med 96 (2022): 87-92.
29. Mason M., et al. “Drug therapy for obstructive sleep apnoea in adults”. Cochrane Database of Systematic Reviews 5 (2023): CD003002.
30. Eskandari D., et al. “Acetazolamide reduces blood pressure and sleep-disordered breathing in patients with hypertension and obstructive sleep apnea: a randomized controlled trial”. Journal of Clinical Sleep Medicine3 (2018): 309-317.
31. Schmidt-Nowara W., et al. “Oral appliances for the treatment of snoring and obstructive sleep apnea: a review”. Sleep 18 (1995): 501-510.
32. Ahrens A., et al. “A systematic review of the efficacy of oral appliance design in the management of obstructive sleep apnoea”. European Journal of Orthodontics 33 (2011): 318-324.
33. Parmenter D and Millar B. “How can general dental practitioners help in the management of sleep apnoea?” British Dental Journal 234 (2023): 505-509.
34. Caples SM., et al. “Surgical modifications of the upper airway for obstructive sleep apnea in adults: a systematic review and meta-analysis”. Sleep10 (2010): 1396-1407.
35. Strollo PJ., et al. “Upper-airway stimulation for obstructive sleep apnea”. The New England Journal of Medicine 2 (2014): 139-149.
36. Kezirian EJ., et al. “Obstructive sleep apnea surgery practice patterns in the United States: 2000 to 2006”. Otolaryngology-Head and Neck Surgery 3 (2010): 441-447.
37. “Patient resource portfolio - Maxillo mandibular advancement, Dept. of otorhinolaryngology, University of Pennsylvania, Penn medicine (2023).
38. Alrejaye NS and Hamdan Al-Jahdali. “Dentists’ role in obstructive sleep apnea: A more comprehensive review”. Sleep Epidemiology 4 (2024): 100073.
39. Quan SF and Schmidt-Nowara W. “The role of dentists in the diagnosis and treatment of obstructive sleep apnea: consensus and controversy”. Journal of Clinical Sleep Medicine 10 (2017): 1117-1119.
40. McNicholas WT and Bonsignore MR. “Management Committee of EU COST ACTION B26. Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities”. European Respiratory Journal 29 (2007): 156-178.
41. Tregear S., et al. “Obstructive sleep apnea and risk of motor vehicle crash: systematic review and meta-analysis”. Journal of Clinical Sleep Medicine 5 (2009): 573-581.
42. Douglas NJ., et al. “Clinical value of polysomnography”. Lancet 339 (1992): 347-350.
43. Anandani A., et al. “Effects of dietary weight loss on obstructive sleep apnea: a meta-analysis”. Sleep Breath 17 (2013): 227-234.
44. Weaver TE and Grunstein RR. “Adherence to continuous positive airway pressure therapy: the challenge to effective treatment”. Proceedings of the American Thoracic Society 5 (2008): 173-178.
45. Ferguson KA., et al. “Oral appliances for snoringand obstructive sleep apnea: a review”. Sleep 29 (2006): 244-262.
46. Greenstone M and Hack M. “Obstructive sleep apnoea”. BMJ 348 (2014): g3745.

Citation

Citation: Chandrasekharan Nair K., et al. “Obstructive Sleep Apnea-A Review".Acta Scientific Dental Sciences 9.4 (2025): 15-25.

Copyright

Copyright: © 2025 Sonia Chauhan., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.