Oral Manifestations of Chronic Kidney Disease - A Research Protocol
Hind Alzahmi*, Lulwa Mohammed and Amna Abdullah
Department of Dentistry, Emirates Health Services, United Arab Emirates
*Corresponding Author: Hind Alzahmi, Department of Dentistry, Emirates Health Services, United Arab Emirates.
Received:
January 07, 2025; Published: January 25, 2025
Abstract
Background: Chronic kidney disease (CKD) is one of the most common global health burdens. This suggests that the oral health
concerns of this population are easily overlooked, particularly among developing countries like the UAE. Hence, the present study
aims to assess the nature and prevalence of oral manifestations among patients with CKD undergoing hemodialysis in the UAE.
Methods: This was a cross-sectional observational study with a mixed-methods approach. A total of 100 CKD patients on hemodialysis for at least one year were recruited from four hospitals in UAE. Data collection involved surveys using questionnaires, clinical oral
examinations, and review of medical records.
Results: The prevalence of a wide range of oral lesions was high, amounting to 73.3%. Periodontal changes were the most prevalent, occurring in 54.0% of subjects, followed by dry mouth in 40.0%, taste changes in 23.0%, and mucosal pallor in 23.0%. There were
weak correlations with patient characterization variables regarding oral lesions, suggesting that oral health challenges may be more
associated with CKD-related factors than demographic characteristics.
Conclusion: The findings underscore the urgent need to integrate comprehensive oral health assessment and care into routine management of patients with CKD in the UAE. Interventions at the practice, organizational, and structural levels will be required, and this
will call for enhanced collaboration between nephrologists and dental professionals to better address the oral health needs of this
patient population and pave ways for evidence-based policy formulation.
Keywords: Oral Manifestation; Chronic Kidney Disease; Research Protocol
References
- Levey AS., et al. “The definition, classification, and prognosis of chronic kidney disease: A KDIGO Controversies Conference report”. Kidney International 80 (2011): 17-28.
- Kovesdy CP. “Epidemiology of chronic kidney disease: an update 2022”. Kidney International Supplements 1 (2022): 7-11.
- Jha V., et al. “Chronic kidney disease: global dimension and perspectives”. The Lancet 382 (2013): 260-272.
- Ansell D and Feest T. “UK Renal Registry Report. UK Renal Registry, Bristol, UK. 5th Annual Report of the Renal Association (2002).
- Sharma P., et al. “Association between periodontitis and mortality in stages 3-5 chronic kidney disease: NHANES III and linked mortality study”. Journal of Clinical Periodontology 43 (2016): 104-113.
- Grau AJ., et al. “Association between acute cerebrovascular ischemia and chronic and recurrent infection”. Stroke 28 (1997): 1724-1729.
- Kshirsagar AV., et al. “Periodontal disease adversely affects the survival of patients with end-stage renal disease”. Kidney International 75 (2009): 746-751.
- Asha V., et al. “Oral manifestations in diabetic and nondiabetic chronic renal failure patients on hemodialysis”. Journal of Indian Academy of Oral Medicine and Radiology4 (2012): 274-279.
- Scully C and Cawson RA. “Genitourinary and renal disease”. Medical Problems in Dentistry. 5th London: Churchill Livingstone (2005): 115-122.
- Mainali A and Chettri PK. “Oral manifestations in hemodialysis patients and their knowledge and attitude towards oral health”. Nepal Medical College Journal4 (2020): 217-222.
- Afroozi B., et al. “Oral findings in hemodialysis patients; a cross-sectional study in Shiraz, Iran”. Journal of Nephropathology 4 (2018): 263-267.
- Craig RG. “Interactions between chronic renal disease and periodontal disease”. Oral Diseases1 (2008): 1-7.
- Eke PI., et al. “Prevalence of periodontitis in adults in the United States: 2009 and 2010”. Journal of Dental Research 91 (2012): 914-920.
- Sunil MK., et al. “Spectrum of orofacial manifestations in renal diseases”. Journal of Orofacial Research 4 (2012): 216-220.
- Kuravatti S., et al. “Oral manifestations of chronic kidney disease-an overview”. International Journal of Contemporary Medical Research4 (2016): 1149-1152.
- Sarumathi T., et al. “Awareness and knowledge of common oral diseases among primary care physicians”. Journal of Clinical and Diagnostic Research 7 (2013): 768-771.
- Rebolledo Cobos M., et al. “Oral health in patients with chronic renal failure hemodialysis after the application of a stomatological protocol”. Advances in Odontostomatology2 (2021): 77-87.
- Lu SY. “Oral candidosis: Pathophysiology and best practice for diagnosis, classification, and successful management”. Journal of Fungi7 (2021): 555.
- Summers SA., et al. “Renal disease and the mouth”. The American Journal of Medicine7 (2007): 568-573.
- Bravo YL., et al. “Oral findings in patients with chronic kidney disease: A cross-sectional descriptive study in Cuenca, Ecuador”. World Journal of Advanced Research and Reviews2 (2021): 373-379.
- Kazdin AE. “Research design in clinical psychology”. Cambridge University Press (2021).
- Browner WS., et al. “Designing clinical research”. Lippincott Williams and Wilkins (2022).
- Portney LG. “Foundations of clinical research: applications to evidence-based practice”. FA Davis (2020).
- Brownson RC., et al. “Dissemination and implementation research in health: translating science to practice”. Oxford University Press (2018).
Citation
Copyright