Bhuvan Nagpal¹, Rujuta Patil², Aparna Pathak³, Geetpriya Kaur⁴* and Shivani Ramesh Mungala⁵

¹Director and Sr. Oral Pathologist, Tohana Manglam Diagnostics, Tohana and Centre for Oral Pathology and Maxillofacial Diagnostics (COPMD)™, Hisar, Haryana, India
²Periodontist, Former Post Graduate Student, Department of Periodontology, The Oxford Dental College, Bangalore, Karnataka, India
³Consultant, Paradise Diagnostics, New Delhi, India
⁴Director, Paradise Diagnostics, New Delhi, India
⁵SVS Institute of Dental Science, Mahabubnagar, Telangana, India

*Corresponding Author: Geetpriya Kaur, Director, Paradise Diagnostics, New Delhi, India.

Received: December 23, 2024; Published: January 04, 2025

Abstract

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a rare, benign, and self-limiting oral mucosal lesion characterized by a persistent, painful, and indolent ulcer. The exact etiology remains unclear, but it is thought to be associated with local trauma or irritation. In this case report, we present the clinical, histopathological, and management aspects of a patient diagnosed with TUGSE. A 70-year-old female patient presented with a chief complaint of a painful ulcer on the left side of the anterolateral aspect of the tongue for the past 10 days. She gave a history of pain being moderate, continuous, and radiating to the cheek. There was no relief post-medication. The histological analysis displayed hyperkeratosis and areas of ulceration with dense inflammatory cells like eosinophils and lymphocytes. There was also evidence of these cells infiltrating tongue musculature. Based on the clinicopathologic features, a diagnosis of Traumatic Ulcerative Granuloma with Stromal Eosinophilia (TUGSE) was rendered. Complete healing was noticed after 1 month. No treatment was required other than regular observation and routine check-ups. The close resemblance of TUGSE to Oral Malignancies makes it challenging to diagnose. Thorough clinical examination and histopathological analysis serve as essential components of the diagnosis of TUGSE. These reactive lesions are self-limiting and respond well to conservative treatment with desired healing.

Keywords: Eosinophilia; Reactive Benign Lesion; Ulcerated Epithelium; Tongue

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Citation

Citation: Geetpriya Kaur., et al. “Traumatic Ulcerative Granuloma with Stromal Eosinophilia (TUGSE)-A Rare Case Report of Diagnostic Dilemma". Acta Scientific Dental Sciences 9.2 (2025): 03-06.

Copyright

Copyright: © 2025 Geetpriya Kaur., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.