Salma BA Abdo¹*, Amera Alkaisi², Vanamala Parthiban³, Aiman Hamad Al koubaisi⁴ and Nouf Ali Salem Alharbi⁵

¹ Consultant Endodontist & Implantologist, Mediclinic Al Madar-AlAin, Abu Dhabi, UAE and AL NAJI University, Bagdad, Iraq
²Maxillofacial Specialist, Department of Dentistry, Al-Mashreq University College, Baghdad, Iraq
³Specialist, Family Medicine Midiclinic Al Madar-AlAin-Abu Dhabi-UAE
⁴Specialist Periodontist and Implantologist, Akil Clinic-Al Ain-Abu Dhabi-UAE
⁵Consultant Endodontist, Heathpoint- Abu Dhabi-UAE

*Corresponding Author: Salma BA Abdo, Consultant Endodontist & Implantologist, Mediclinic Al Madar-AlAin, Abu Dhabi, UAE and AL NAJI University, Bagdad, Iraq.

Received: December 03, 2024; Published: December 17, 2024

Abstract

Objective: The goal of this study was to compare concentrated platelet-rich plasma (cPRP) with a blood clot (BC) or a blood clot (BC) alone in the regeneration of non-vital pulp tissue in teeth with apical periodontitis clinically and radiologically.

Materials and Methods: Twenty-four children with an open apex and necrotic pulp with acute apical periodontitis were divided into two groups, A and B, and included in this study. On the first visit, the pulp chamber was accessed, a file loosely positioned 1 mm from the root apex, the canal was irrigated copiously with sodium hypochlorite using a needle positioned approximately 1 mm from the root apex, and the canal was dried. The canal was filled with calcium hydroxide as an intracanal medicament, and a glass ionomer was used for temporary restoration. The second visit started after 4 weeks. The canal was reopened, cleaned and dried. Bleeding was intentionally induced by using 25 files 2 mm beyond the apex into the canal. Then, cPRP gel was applied to the intracanal cementoe namel junction for Group A only. The canal was sealed with a 3-mm-thick layer of MTA, and the teeth were filled with composite for Groups A and B.

Results: SPSS version 26 was used for data analysis via the chi-square test, and a p value less than 0.05 was considered statistically significant. Within two years of follow-up, all teeth showed resolution of periapical radiolucency, continued root development with a positive response to the sensibility cold test and no discolouration in Group (A). In Group (B), 3 teeth failed.

Conclusion: Our results confirmed the previous finding that cPRP with BC regenerates pulp tissue and is a better method for tissue engineering than BC alone.

Keywords: Blood Clots; Concentrated Platelet-Rich Plasma; Regenerative Endodontic Treatment

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Citation

Citation: Salma BA Abdo., et al. “The Efficiency of CPRP and Blood Clots in Regeneration of Non-Vital Pulp Tissue in Teeth with Periapical Periodontitis Compared to Blood Clot Alone". Acta Scientific Dental Sciences 9.1 (2025): 24-29.

Copyright

Copyright: © 2025 Salma BA Abdo., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.