A Concise Review of Immune Checkpoint Inhibitors Immunotherapy for Head and Neck Cancer
Mutaz Fahad Felemban1, Azizah Fahad Bin Mubayrik2* and Hael Hani Mukhtar3
1Graduate Student, Doctor of Science in Dentistry Oral Medicine Track, College of Dentistry, King Saud University, Saudi Arabia
2Division of Oral Medicine, Department of Oral medicine and Diagnostic Sciences,
College of Dentistry, King Saud University, Saudi Arabia
3Graduate student, Doctor of Science in Dentistry Oral Medicine Track, College of Dentistry, King Saud University, Saudi Arabia
*Corresponding Author: Azizah Fahad Bin Mubayrik, Division of Oral Medicine, Department of Oral medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Saudi Arabia.
Received: December 04, 2023; Published: December 20, 2023
Abstract
Tumor cells can evade and suppress immune response through various mechanisms such as T cell activation suppression by PD-1 and/or CTLA-4. The main objective of this study is to examine the checkpoint inhibitors immunotherapy for head and neck cancer. Data were collected in numerous areas from various medical databases. The data collected and were thoroughly analyzed. Major findings of the studies were analyzed and presented in this article. Conclusions: The findings showed that immunotherapy is promising to increase survival rate and control of metastasis.
Keywords:Cancer Immunotherapy; Immune Checkpoint Inhibitors; Head and Neck Cancer; Monoclonal Antibodies Therapy; Cytokines Immunothearpy
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