Sumana Bhowmick*

Medical Officer, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

*Corresponding Author: Sumana Bhowmick, Medical Officer, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

Received: October 16, 2023; Published: October 29, 2023

Abstract

Background: Oral Squamous Cell Carcinoma (OSCC) represents a significant portion of head and neck malignancies, with high morbidity and mortality rates. Despite advancements in therapies, OSCC remains challenging due to local invasion and recurrence. The retro-molar trigone (RMT), an area overlying the mandible, is susceptible to aggressive bone invasion and poor prognosis of OSCC. However, factors contributing to local recurrence are poorly understood.

Methods: An investigation based on prospective observation occurred at Dhaka Dental College and Hospital, involving thirty-five patients with histopathologically confirmed OSCC between March 2017 and August 2018. Detailed information was gathered regarding patient attributes, habits, tumor characteristics, clinical and pathological stages, and postoperative treatments. The data underwent statistical analysis using SPSS version 26 to discern noteworthy risk factors linked to local recurrence.

Results: Patients had a mean age of 50.37±9.49 years, with a significant proportion (37.1%) falling within the 41-50 age group. Gender distribution revealed a 1:1.5 male-to-female ratio among 35 subjects. Habits such as betel quid use and smoking were prevalent, and co-morbidities like hypertension (34.3%) and diabetes mellitus (20.0%) were notable. Tumor characteristics showed a majority with T2 tumors (54.3%), while clinical staging indicated that most patients presented at an advanced stage, with 60% classified as stage III. Notably, our analysis revealed a significant correlation between clinical stage IV and recurrence (p = 0.03), emphasizing the importance of staging and adjuvant therapy in managing OSCC in this region.

Conclusions: Recurrence of OSCC in the retro-molar trigone is influenced by clinical, pathological, and histological factors. The study underlines the significance of accurate staging, margin evaluation, and appropriate postoperative therapy for effective management. Identifying these risk factors can aid in devising strategies to reduce local recurrence in OSCC patients undergoing radical surgery

Keywords: OSCC Recurrence; Retro-Molar Trigone; Clinical Factors; Lymph Node Metastasis

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Citation

Citation: Sumana Bhowmick. “Clinical Risk Factors for Local Recurrence of Oral Squamous Cell Carcinoma in Retro-Molar Trigone at a Tertiary Level Hospital".Acta Scientific Dental Sciences 7.11 (2023): 79-84.

Copyright

Copyright: © 2023 Sumana Bhowmick. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.