Acta Scientific Dental Sciences (ASDS)(ISSN: 2581-4893)

Research Article Volume 7 Issue 11

Comparative Evaluation of Analgesic Effect of 4% Articaine with 2% Lignocaine in Surgical Extraction of Mandibular Third Molar: A Randomised Prospective Clinical Trial

Pooja Gopal Choudhary1*, Francis Akkara2, Vikas Dhupar3 and Rakhi Shende4

1Department of Oral and Maxillofacial Surgery, Goa Dental College and Hospital, Bambolim, Goa, India
2Professor, OMFS, Goa Dental College and Hospital, Bambolim, Goa, India
3Professor and HOD, OMFS, Goa Dental College and Hospital, Bambolim, Goa, India

*Corresponding Author: Pooja Gopal Choudhary, Department of Oral and Maxillofacial Surgery, Goa Dental College and Hospital, Bambolim, Goa, India.

Received: October 06, 2023; Published: October 25, 2023


Background: Surgical extraction of impacted third molar is one of the most common surgical procedure performed by a maxillofacial surgeon [1]. To provide a pain-free treatment to patients, numerous local anesthetic agents has been used by surgeon. However, gold standard has been lignocaine hydrochloride [2]. In spite of introduction in 1976, articaine is not renowned in dentistry. In this randomised clinical trial, we aimed to determine the safety and efficacy of articaine in comparison with lignocaine for surgical extraction of impacted mandibular third molar.

Method: The study was done in the department of OMFS on 50 patients of age between 18 and 40 years of both genders receiving either 4% articaine hydrochloride (HCl) with 1: 100,000 epinephrine or 2% lignocaine HCl with 1: 200,000 epinephrine. Drug volume, onset of anaesthesia, duration of anaesthesia and duration of postoperative analgesia intake with post-extraction sequels were evaluated for both groups with follow up till 7 post operative days. The parametric and non-parametric test used to analyse data using SPSS Statistics 21.0 program.

Result: 50 patients included in the study out of which 19 were female and 31 males, underwent surgical extraction performed by the same oral surgeon. Age range was 18 to 60 with a peak incidence in the age group of 18-30 years. The author found statistically significant difference between study groups in relation to mean volume (articaine - 2.07 ± 0.37 ml and lignocaine - 3.48 ± 0.85 ml, P value-0.00).

Conclusion: The efficacy of 4% articaine is comparable with that of 2% lignocaine and hence, can be used as an alternative to lignocaine in surgical extraction of mandibular third molar.

Keywords: Local Anesthesia; Lignocaine; Articaine


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Citation: Pooja Gopal Choudhary., et al. “Comparative Evaluation of Analgesic Effect of 4% Articaine with 2% Lignocaine in Surgical Extraction of Mandibular Third Molar: A Randomised Prospective Clinical Trial".Acta Scientific Dental Sciences 7.11 (2023): 53-58.


Copyright: © 2023 Pooja Gopal Choudhary., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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