Acta Scientific Dental Sciences (ASDS)(ISSN: 2581-4893)

Case Report Volume 7 Issue 9

Mycobacterium Abscessus Infection Following Injections of Botulinum Toxin: A Report of Two Cases

Luisa Machado Barin1*, Kathleen Jarmendia Costa2 and Isabela Reginaldo2

1Professor, Department of Dentistry, Federal University of Santa Catarina, Florianópolis, SC, Brazil
2Graduate, Department of Dentistry, Federal University of Santa Catarina, Florianópolis, SC, Brazil

*Corresponding Author: Luisa Machado Barin, Professor, Department of Dentistry, Federal University of Santa Catarina, Florianópolis, SC, Brazil.

Received: August 04, 2023; Published: August 23, 2023

Abstract

Botulinum Toxin A has become popular worldwide and is considered a safe treatment protocol. The complications are usually transient and minimal. Injection site infections or long-term reactions are rare. Here, we report 2 cases of Mycobacterium abscessus infection following injection of botulinum toxin of dramatic clinical repercussions and prolonged treatment. Case 1, a 61-year-old woman after receiving botulinum injections presented papules and nodules in her forehead and periorbital areas and diffuse frontal edema. Papules became erythematous nodules, and purulent drainage occurred. The lesions did not show any alleviation after the prescription of corticosteroids and broad-band antibiotics. The incisional biopsy of skin tissue showed inflammatory cell infiltration. Afterward, the puncture on the abscess was performed and Mycobacterium abscessus was successfully isolated. The patient was treated with the strategy of linezolid, cefoxitin, and amikacin, according to the result of the drug sensitivity test. The treatment lasted five months and led to an aesthetic sequel. Case 2, a 31-year-old woman after three days of receiving facial botulinum injections presented violaceous and fibrous nodules. Laboratory tests also showed Mycobacterium abscessus. The patient was treated with linezolid, tigecycline, and amikacin and got complete remission of the lesions after four months. The consequences caused by aesthetic procedures are rarely discussed and can significantly impact the patient's self-esteem and physical and psychological status.

Keywords: Botulinum Toxin; Infection; Mycobacterium Abscessus; Nontuberculous Mycobacterium

References

  1. Mendez-Eastman SK. “BOTOX: a review”. Plastic and Aesthetic Nursing 2 (2003): 64-69.
  2. Thanasarnaksorn W., et al. “Botulinum toxin type A injection-related suppurative granuloma: a case report”. Journal of Cosmetic and Laser Therapy 7-8 (2019): 422-424.
  3. Cote TR., et al. “Botulinum toxin type A injections: adverse events reported to the US Food and Drug Administration in therapeutic and cosmetic cases”. Journal of the American Academy of Dermatology 53 (2005): 407-415.
  4. Yun WJ., et al. “The first documented case of true botulinum toxin granuloma”. Journal of Cosmetic and Laser Therapy 6 (2013): 345-347.
  5. Hartmann D., et al. “Complications associated with cutaneous aesthetic procedures”. Journal Der Deutschen Dermatologischen Gesellschaft 13 (2015): 778-786.
  6. Chen X., et al. “Mycobacterium abscessus cutaneous infection secondary to botulinum toxin injection: A report of 2 cases”. JAAD Case Reports 11 (2019): 982-984.
  7. Saeb-Lima M., et al. “Mycobacterial infection after cosmetic procedure with botulinum toxin a”. Journal of Clinical and Diagnostic Research 4 (2015): WD01-2.
  8. Lee MR., et al. “Mycobacterium abscessus Complex Infections in Humans”. Emerging Infectious Diseases9 (2015): 1638-1646.
  9. Griffith DE., et al. “An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases”. American Journal of Respiratory and Critical Care Medicine 175 (2007): 367-416.
  10. Assmann T., et al. “Cutaneous sarcoidal granuloma after botulinum toxin type A injection”. Journal of the American Academy of Dermatology 5 (2013): e247-e249.

Citation

Citation: Luisa Machado Barin., et al. “Mycobacterium Abscessus Infection Following Injections of Botulinum Toxin: A Report of Two Cases".Acta Scientific Dental Sciences 7.9 (2023): 91-94.

Copyright

Copyright: © 2023 Luisa Machado Barin., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.278

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