Aguzzi Alejandra¹*, Virga Carolina¹, De Leonardi Gabriela¹, Briner Garrido Michelle² and Moro Cecilia¹

¹Oral Pathology, National University of Cordoba School of Dentistry, Argentina
²Department of Oral Pathology, Radiology and Medicine, University of Missouri-Kansas City

*Corresponding Author: Aguzzi Alejandra, Oral Pathology, National University of Cordoba School of Dentistry, Argentina.

Received: May 15, 2023; Published: June 16, 2023

Abstract

Introduction: The maintenance of bone mass in the jaws has always been a concern for dental professionals, as it is essential for teeth and implants support.

Objective: To study the effect of local administration of Alendronate sodium (AL) and Aloe vera (VA) on tissue regeneration of the post-extraction socket of the lower first molars in rats.

Materials and Methods: The experimental rats were divided into groups, depending on the drug combination they would receive. Four groups were formed: Control (saline solution), Alendronate sodium (0.5mg/Kg of weight), Aloe vera (at 70% concentration) and Alendronate sodium+Aloe vera (0.5mg/Kg of weight + 70% Aloe vera). The rat’s lower first molars were extracted, then gelatin sponges soaked in the experimental drugs were placed into the extraction socket. The handling of the animals was carried out following the norms established by SECyT according to the Institutional Committee for the care and use of laboratory animals. Radiographs of the jaws were taken at 0, 15, 30 and 60 days with a radiovisiograph (Sirona Xios) and analyzed with the ProPlus Image Software version 4.1. Data were analyzed by ANOVA test.

Results: In the radiographic study, at 30 days a significant increase in bone mineral density was evidenced in the AV group compared to the C group (p <0.01).

Conclusions: The data suggest that the process of new bone formation would be more accelerated in the Aloe vera and Alendronate sodium+Aloe vera groups given the higher optical density recorded in the 30-day stage in contrast to the Alendronate sodium alone and the control groups.

Keywords: Alendronate; Aloe vera; Bone Remodeling

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Citation

Citation: Aguzzi Alejandra.,et al. “Radiographic Study of the Post-Extraction Socket: Local Effect of Alendronate and Aloe vera".Acta Scientific Dental Sciences 7.7 (2023): 29-35.

Copyright

Copyright: © 2023 Aguzzi Alejandra., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.