A Review on Salivary Genomics in Oral Cancer
Mithlesh Solanki, Sangeeta R Patankar and Gokul Sridharan*
Department of Oral Pathology and Microbiology, Dr. G. D. Pol Foundation YMT Dental College and Hospital, Navi Mumbai, India
*Corresponding Author: Gokul Sridharan, Department of Oral Pathology and Microbiology, Dr. G. D. Pol Foundation YMT Dental College and Hospital, Navi Mumbai, India.
Received: May 08, 2023; Published: May 28, 2023
Oral cancer has emerged as a distressing health problem with increasing incidence and mortality rates all over the world. Early diagnosis and prompt treatment are the need of the hour to reduce the morbidity and mortality rate. The use of tumor biomarkers in disease diagnostics has garnered importance in recent times owing to advancements in technologies used for the identification of such biomarkers. OMICS technologies such as genomics, proteomics, transcriptomics and metabolomics have been used to detect various biomarkers in oral cancer and pre-cancer. The use of saliva for the identification of tumor biomarkers is promising owing to the ease of collection and the close proximity to the oral lesions. The present review highlights the importance of salivary genomic biomarkers in oral carcinogenesis.
Keywords: Oral Cancer; Salivary Diagnostics; Genomics; Oral Pre-Cancer
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