Acta Scientific Dental Sciences (ASDS)(ISSN: 2581-4893)

Review Article Volume 7 Issue 6

Rheumatic Fever, A Review of the Literature

Przemyslaw Kustra*

Department of Conservative Dentistry with Endodontics, Jagiellonian University of Medical College, Poland

*Corresponding Author: Przemyslaw Kustra, Department of Conservative Dentistry with Endodontics, Jagiellonian University of Medical College, Poland.

Received: April 25, 2023; Published: May 15, 2023


Rheumatic fever (RF) is a multi-organ inflammatory disease that develops on an autoimmune basis as a response to throat infection with group A beta-hemolytic Streptococci in individuals of a particular predisposition. It is revealed, on average, in the 3rd week of the asymptomatic latency period after throat infection, in the form of carditis, arthritis, chorea minor, skin and soft tissue reactions, leaving permanent sequelae only in the area of the heart. The natural course of RF is characterized by relapses, which are a clinical reproduction of the first course of the disease.

The highest incidence of RF involves the population with the highest risk of streptococcal pharyngitis, i.e., children aged 5-15 years, with a peak between the ages of 10 and 12 years, with no gender-related differences. Disease also occurs among younger children as well as adults. Fresh cases of RF in Poland are now encountered only sporadically, and the picture and clinical course of the disease have become considerably milder in the last two decades.

 Keywords: Rheumatic Fever; Streptococcus; Streptococci


  1. Azevedo PM., et al. “Understanding rheumatic fever”. Rheumatology International 32 (2012): 1113-1120.
  2. Gevitz MH. et al. “Revision of the Jones Criteria for the Diagnosis of Acute Rheumatic Fever in the Era of Doppler Echocardiography”. Circulation 131 (2015): 1806-1818.
  3. Carapetis JR., et al. “Acute rheumatic fever”. Lancet 366 (2005): 155-168.
  4. No authors listed. “JONES CRITERIA (modified) for guidance in the diagnosis of rheumatic fever”. Public Health Reports (1896-1970) 7 (1956): 672-674.
  5. Ralph AP., et al. “The 2020 Australian guideline for prevention, diagnosis and management of acute rheumatic fever and rheumatic heart disease”. The Medical Journal of Australia 214 (2021): 220-227.
  6. Holloway AR. “Acute Rheumatic Fever”. Pediatric Annals 51 (2022): e457-e460.
  7. Lahiri S., et al. “Acute Rheumatic Fever”. Pediatrics In Review 42 (2021): 221-232.
  8. Gibofsky A., et al. “Rheumatic fever and poststreptococcal reactive arthritis”. Current Opinion in Rheumatology 7 (1995): 299-305.
  9. Jaggi P. “Rheumatic Fever and postgroup-a streptococcal arthritis”. The Pediatric Infectious Disease Journal 30 (2011): 424-425.
  10. Sika-Paotonu D. “Acute Rheumatic Fever and Rheumatic Heart Disease”. Streptococcus pyogenes: Basic Biology to Clinical Manifestations (2016).
  11. Burke RJ. “Diagnostic criteria of acute rheumatic fever”. Autoimmunity Reviews 13 (2014): 503-507.
  12. Cherkashin DV. “Rheumatic fever”. Klin Med 91 (2013): 4-12.
  13. Miller LC. “Rheumatic fever, reactive arthritis, and musculoskeletal infections in children”. Current Opinion in Rheumatology 3 (1991): 826-831.
  14. Arvind B., et al. “Rheumatic Fever and Rheumatic Heart Disease in Children”. Indian Journal of Pediatrics 87 (2020): 305-311.
  15. Stollerman GH. “Rheumatic fever”. Lancet 349 (1997): 935-942.


Citation: Przemyslaw Kustra. “Rheumatic Fever, A Review of the Literature”. Acta Scientific Dental Sciences 7.6 (2023): 14-20.


Copyright: © 2023 Przemyslaw Kustra. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.278

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is April 30th, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US