Bharat Patodiya¹*, Shalini Patodiya², Shivam Shingla³ and Sudha Sinha⁴

¹Consultant, Department of Oncology, AIG Hospitals, Hyderabad, Telangana, India ²Consultant Dermatologist Citizens Hospital, Hyderabd Telangana, India ³Consultant Medical Oncologist, Nanavati Max Hospital, Mumbai, India ⁴Senior Medical Oncologist, Care Hospital, Hyderabad, Telangana, India

*Corresponding Author: Bharat Patodiya, Consultant, Department of Oncology, AIG Hospitals, Hyderabad, Telangana, India.

Received: September 27, 2022; Published: October 12, 2022

Abstract

Prior to beginning treatment, it is essential that a multidisciplinary tumour board discuss each patient's situation and devise a treatment plan for oral cavity squamous cell carcinoma (OSCC), a heterogeneous illness. One of the common postoperative consequences following oral cancer surgery is an orocutaneous fistula (OCF). This incident broadens the amount of knowledge on OCF regression after adjuvant therapy. It is also important not to give up on a relpased oncology case, just on the basis of age of the patient.

Keywords: Oral Cavity Squamous Cell Carcinoma; Orocutaneous Fistula; Hemi Mandibulectomy; Radiation; Adjuvant Therapy; Afatinib; Metronomic Targeted Frug

References

1. Santos HB., et al. “Clinical findings and risk factors to oral squamous cell carcinoma in young patients: A 12-year retrospective analysis”. Medicina Oral, Patología Oral y Cirugía Bucal 2 (2016): e151-e156.
2. Shah JP and Gil Z. “Current concepts in management of oral cancer-surgery”. Oral Oncology 4-5 (2009): 394-401.
3. Huang SH and O'Sullivan B. “Oral cancer: Current role of radiotherapy and chemotherapy”. Medicina Oral, Patología Oral y Cirugía Bucal 2 (2013): e233-e240.
4. Fang Q., et al. “Orocutaneous Fistula Formation in Free Flap Reconstruction for Oral Squamous Cell Carcinoma”. Frontiers in Oncology 12 (2022): 887118.
5. Markopoulos AK. “Current aspects on oral squamous cell carcinoma”. The Open Dentistry Journal 6 (2012): 126-130.
6. Oral cancer - the fight must go on against all odds”. Evidence-Based Dentistry 23 (2022): 4-5.
7. Chouk C and Litaiem N. “Oral Cutaneous Fistula”. In: StatPearls. Treasure Island (FL): StatPearls (2022).
8. Mendenhall WM., et al. “Postoperative radiotherapy for squamous cell carcinoma of the head and neck”. Clinical Medicine and Research 3 (2006): 200-208.
9. Borgonovo AE., et al. “Surgical options in oroantral fistula treatment”. The Open Dentistry Journal 6 (2012): 94-98.
10. Suárez C., et al. “Carotid blowout syndrome: modern trends in management”. Cancer Management and Research 10 (2018): 5617-5628.
11. Girkar F., et al. “Factors Predisposing to the Development of Orocutaneous Fistula Following Surgery for Oral Cancer: Experience from a Tertiary Cancer Center”. Head Neck 41 (2019): 4121–7.
12. Hasan MY., et al. “Negative-pressure wound therapy for management of diabetic foot wounds: a review of the mechanism of action, clinical applications, and recent developments”. Diabetic Foot and Ankle 6 (2015): 27618.
13. Tang X., et al. “Response to nivolumab combining radiotherapy and nimotuzumab in metastatic oral squamous cell carcinoma patient with strong PD-L1 expression: a case report”. Annals of Translational Medicine 6 (2020): 402.
14. Simsek C., et al. “Metronomic Chemotherapy: A Systematic Review of the Literature and Clinical Experience”. Journal of Oncology 2019 (2019): 5483791.
15. Yamaoka T., et al. “Receptor Tyrosine Kinase-Targeted Cancer Therapy”. International Journal of Molecular Sciences 11 (2018): 3491.

Citation

Citation: Bharat Patodiya., et al. “Complete Clinical Regression of Orocutaneous Fistula in Contralateral Relpased Oral Cavity Squamous Cell Carcinoma Patient Following Surgery and Adjuvant Radiotherapy". Acta Scientific Dental Sciences 6.11 (2022): 34-37.

Copyright

Copyright: © 2022 Bharat Patodiya., et al.. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.