Simran Verma*, Bhakti Soman Patil and Deepa Das

Department of Oral Medicine and Maxillofacial Radiology, Dr. G. D. Pols Foundation's YMT Dental College and Hospital, India

*Corresponding Author: Simran Verma; Department of Oral Medicine and Maxillofacial Radiology, Dr. G. D. Pols Foundation's YMT Dental College and Hospital, India.

Received: September 15, 2022; Published: October 06, 2022

Abstract

Deflazacort is a synthetic corticosteroid characterized by its favorable pharmacokinetic profile, distinct pharmacodynamic properties and a good safety profile when compared to other corticosteroids. Few of the substantial potential properties of this drug include lack of sodium- retaining activity, strong anti- inflammatory/immunosuppressive activity, and lower interference with carbohydrate metabolism and phosphocalcium metabolism in comparison with older corticosteroids. They have always formed an important component of dermatological therapy, but recently has gained importance to be used as a therapeutic drug to treat various oral mucosal lesions. Here, we also reported a case of erosive lichen planus in a 40-year-old man who was treated with deflazacort. He was managed with tapering systemic doses of deflazacort, following which there was complete remission of the lesions.

Keywords: Deflazacort; Adverse Effects; Oral Lichen Planus; Immunosuppressants; Autoimmune; Glucose Metabolism

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Citation

Citation: Simran Verma., et al. “Deflazacort Paving its Way in the Treatment of Oral Lesions- Review and A Case Report". Acta Scientific Dental Sciences 6.11 (2022): 21-24.

Copyright

Copyright: © 2022 Simran Verma., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.