Seema Deshmukh¹, Sowmya Srinivas²*, Sushma Rudraswamy³, Nagabhushana Doggalli⁴, Raghavendra Swamy KN⁵ and Indira⁶

¹Department of Pedodontics and Preventive Dentistry, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), Mysuru, Karnataka, India
²Senior Lecturer, Department of Prosthodontics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), Mysuru, Karnataka, India
³Senior Lecturer, Department of Public Health Dentistry, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), Mysuru, Karnataka, India
⁴Department of Oral Medicine and Radiology, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), Mysuru, Karnataka, India
⁵Professor and HOD, Department of Prosthodontics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), Mysuru, Karnataka, India
⁶Senior Lecturer, Department of Pedodontics and Preventive Dentistry, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), Mysuru, Karnataka, India

*Corresponding Author: Sowmya Srinivas, Senior Lecturer, Department of Prosthodontics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), SS Nagar, Mysuru, Karnataka, India.

Received: July 14, 2022; Published: July 26, 2022

Abstract

The period of nanomaterial has an enduring impact in the field of medical care. Its magnificent use in medical science has led to its utilization in dentistry. Microbial biofilms elimination from oral cavity still exists as a great concern in the field of dentistry. In the process of elimination of biofilms, the nano material compared to conventional materials have proven to be much more structured with efficient bonding capabilities and good chemical science. The nanomaterial of the drugs used for therapeutic purposes have various advantages which included increased bioavailability, prevention of micro leakage and may also provide preventive benefits. Nanoparticles incorporated dental materials also present with improved mechanical properties such as increased fracture toughness, decreased crack propagation and improved bonding to the tooth structure. The advantage of preparing propolis nanoparticles could be that this process helps in protection of the active ingredient from degradation and also may provide sustained release.

Studies on nanoparticles have been carried out using metallic material but there are very few or limited literature on natural products especially propolis nanoparticle. Hence this review attempts to describe the uses of propolis in the nanoparticle form for dental applications.

Keywords:Nanoparticles; Propolis; Antimicrobial Effect; Dental Use

References

1. Foong LK., et al. “Applications of nano-materials in diverse dentistry regimes”. RSC Advances26 (2020): 15430-15460.
2. Pinheiro Machado GT., et al. “Development of propolis nanoparticles for the treatment of bovine mastitis: in vitro studies on antimicrobial and cytotoxic activities”. Canadian Journal of Animal Science 4 (2019): 713-723.
3. Savoia D. “Plant-derived antimicrobial compounds: alternatives to antibiotics”. Future Microbiology 8 (2012): 979e90.
4. Spellberg B., et al. “Novel approaches are needed to develop tomorrow's antibacterial therapies”. American Journal of Respiratory and Critical Care Medicine 2 (2015): 135-140.
5. Przybyłek I and Karpiński TM. “Antibacterial Properties of Propolis”. Molecules11 (2019): 2047.
6. Croteau TM., et al. “Natural Products (Secondary Metabolites)”. Biochemistry and Molecular Biology of Plants, American Society of Plant Physiologists, Rock Ville (2000): 1250-1318.
7. Erler S and Moritz RFA. “Pharmacophagy and pharmacophory: mechanisms of self-medication and disease prevention in the honeybee colony (Apis mellifera)”. Apidologie 47 (2016): 389-411.
8. Middleton E. “Effect of plant flavonoids on immune and inflammatory cell function”. Advances in Experimental Medicine and Biology 439 (1998): 175-182.
9. Molan PC. “The potential of honey to promote oral wellness”. General Dentistry 49 (2001): 584-589.
10. Park YK., et al. “Botanical origin and chemical composition of Brazilian propolis”. Journal of Agricultural and Food Chemistry 50 (2002): 2502-2506.
11. Silva-Carvalho R., et al. “Propolis: A complex natural product with a plethora of biological activities that can be explored for drug development”. Evidence-Based Complementary and Alternative Medicine (2015).
12. Silva BB., et al. “Chemical composition and botanical origin of red propolis, a new type of Brazilian propolis”. Evidence-Based Complementary and Alternative Medicine 103 (2008): 487-492.
13. Stefan Bogdanov. “Propolis: Composition, Health, Medicine: A Review”. Bee Product Science (2016).
14. GA Burdock. “Review of the biological properties and toxicity of bee propolis”. Food and Chemical Toxicology4 (1998): 347-363.
15. Menniti-Ippolito F., et al. “Surveillance of suspected adverse reactions to natural health products: the case of propolis”. Drug Safety 31 (2008): 419-423.
16. Hay KD and Greig DE. “Propolis allergy: a cause of oral mucositis with ulceration”. Oral Surgery, Oral Medicine, Oral Pathology 70 (1990): 584-586.
17. Budimir V., et al. “Allergic contact cheilitis and perioral dermatitis caused by propolis: case report”. Acta Dermatovenerologica Croatica 20 (2012): 187-190.
18. Nascimento., et al. “Polymeric Nanoparticles of Brazilian Red Propolis Extract: Preparation, Characterization, Antioxidant and Leishmanicidal Activity”. Nanoscale Research Letters1 (2016): 301.
19. Grenho L., et al. “In vitro antimicrobial activity and biocompatibility of propolis containing nanohydroxyapatite”. Biomedical Materials 2 (2015): 025004.
20. Sodagar A., et al. “Evaluation of the Effect of Propolis Nanoparticles on Antimicrobial Properties and Shear Bond Strength of Orthodontic Composite Bonded to Bovine Enamel”. Frontiers in Dentistry2 (2019): 96-104.
21. Afrasiabi S., et al. “Propolis nanoparticle enhances the potency of antimicrobial photodynamic therapy against Streptococcus mutans in a synergistic manner”. Scientific Reports 10 (2020): 15560.
22. Parolia A., et al. “Effect of Propolis Nanoparticles against Enterococcus faecalis Biofilm in the Root Canal”. Molecules 3 (2021): 715.
23.  

Citation

Citation: Sowmya Srinivas.,et al. “Nature’s Natural Antimicrobial Agent “Propolis Nanoparticle”-Mini Review".Acta Scientific Dental Sciences 6.8 (2022): 121-124.

Copyright

Copyright: © 2022 Sowmya Srinivas., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.