Acta Scientific Dental Sciences (ISSN: 2581-4893)

Research Article Volume 6 Issue 8

Evaluation of Effect of PRF on Rebound of Soft Tissue in Immediate Placement of Implants-A Randomized Control Study

Kambagouni Chandana1, S Rakesh Kumar1*, CH Siva Krishna2, Sirisha Mekala1, M Lakshmi Durga1 and Bangaru Mounika1

1Department of Public Health Dentistry, Private Dental Practitioner, Hyderabad, India
2Department of Oral & Maxillofacial Surgery, Assistant Professor at Kamineni Institute of Dental sciences, Narketpally, Nalgonda, Telangana, India
3Department of Periodontology and Implantology, Private Dental Practitioner, Guntur, India

*Corresponding Author: S Rakesh Kumar, Department of Periodontology and Implantology, Private Dental Practitioner, India.

Received: July 08, 2022; Published: July 26, 2022

Abstract

Aims and objectives: To evaluate the effect of Platelet Rich Fibrin (PRF) on rebound of soft tissue in immediate placement of implants and revaluate at 3 months, 6months and 9months. Objectives of the study are to clinically evaluate the thickness of soft tissue, to evaluate the implant mobility and to evaluate peri implant radiolucency.

Methodology: 11 patients from the Department of Periodontics at the Government Dental College and Hospital in Hyderabad participated in the current clinical study in order to receive implants right away. The MYRIAD IMPLANT SYSTEM was the implant system utilised for this study. The application of PRF around the immediate implant led to the division of the subjects into Group I and Group II. The study was conducted for 9 months after receiving approval from the institutional ethical committee. Every patient had their case history filled out in-depth on a unique proforma. Patient was called back three, six, and nine months after the implant was placed for clinical and radiographic evaluation. Later descriptive statistical analysis had been done.

Results: Group I (PRF): The WKS at baseline was 4.03 ± 0.16 and increased to 4.05 ± 0.18 after three months, 4.08 ± 0.13 after six months, and 4.17 ± 0.10 after nine months. The WKS in Group II (without PRF) was 4.02 ± 0.16 at baseline, 4.00 ± 0.11 at three months, 4.07 ± 0.12 at six months, and 4.08 ± 0.10 at nine months. In this study, all 12 implants that were placed right away demonstrated good stability, no implant mobility, and no peri-apical radiolucency during the nine-month postoperative follow-up period.

Conclusion: The width of the keratinized soft tissue increased when compared to the control group. In the group without PRF, the width of keratinized soft tissue did not increase. When compared to Group II, Group I (PRF) showed a statistically significant increase in the width of keratinized soft tissue (without PRF). The study's findings show that Group I (PRF) soft tissue has thicker tissue than Group II, a difference that is statistically significant (without PRF).

Keywords:PRF; Soft Tissue; Placement; Implants

References

  1. Horwitz J and Machtei E. “Immediate and Delayed Restoration of Dental Implants in Patients with a History of Periodontitis: A Prospective Evaluation up to 5 Years”. The International Journal of Oral and Maxillofacial Implants 27 (2012): 1137-1143.
  2. Wilson T and Buser D. “Timing of Anterior Implant Placement Post extraction: Immediate Versus Early Placement”. Clinical Advances in Periodontics1 (2011): 61-74.
  3. Schropp L., et al. “Bone Healing Following Immediate Versus Delayed Placement of Titanium Implants into Extraction Sockets: A Prospective Clinical Study”. The International Journal of Oral and Maxillofacial Implants 18 (2003): 189-199.
  4. Pragathi R., et al. “The influence of soft tissue biotype on the marginal bone changes around dental implants. A 1-year prospective clinic radiological study”. Journal of Indian Society of Periodontology 19 (2015): 640-644.
  5. Swathi S., et al. “Measurement of gingival thickness using digital vernier caliper and ultrasonographic method. A comparative study”. Journal of Investigative and Clinical Dentistry 5 (2014): 138-143.
  6. Jia Hui F., et al. “Tissue biotype and its relation to the underlying bone morphology”. Journal of Periodontology 81 (2010): 569-574.
  7. Carios FAB and Natalia B. “Platelet rich membrane in immediate dental implant loading”. Dental Press Implantology 9 (2015): 104-109.
  8. Elif O and Emine A. “The effect of platelet rich fibrin on implant stability”. The International Journal of Oral and Maxillofacial Implants 30 (2015): 578-582.
  9. Dohan DM., et al. “Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part II: Platelet-related biologic features”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 101 (2006): 45-50.
  10. Anand U and Mehta DS. “Evaluation of Immediately Loaded Dental Implants Bioactivated with Platelet-Rich Plasma Placed in the Mandibular Posterior Region: A Clinico-Radiographic Study”. Journal of Indian Society of Periodontology1 (2012): 89-95.
  11. Viswambaran CM., et al. “Clinical evaluation of immediate implants using different types of bone augmentation materials”. Medical Journal Armed Forces India 70 (2014): 154-162.
  12. Hartog L., et al. “Treatment outcome of immediate, early and conventional single-tooth implants in the aesthetic zone: a systematic review to survival, bone level, soft-tissue, aesthetics and patient satisfaction”. Journal of Clinical Periodontology 35 (2008): 1073-1086.
  13. Schropp L and Isidor F. “Timing of implant placement relative to tooth extraction”. Journal of Oral Rehabilitation 1 (2008): 33-43.
  14. Covani U., et al. “Bucco-Lingual Crestal Bone Changes After Immediate and Delayed Implant Placement”. Journal of Periodontology 75 (2004): 1605-1612.
  15. Tomasi C., et al. “Bone dimensional variations at implants placed in fresh extraction sockets: a multilevel multivariate analysis”. Clinical Oral Implants Research 1 (2010): 30-36.
  16. Kenawy EL., et al. “Efficacy of Platelet Rich Fibrin (PRF) Membrane in Immediate Dental Implant”. Mansoura Journal of Dentistry 3 (2001): 78-84.
  17. Gomez-Roman G., et al. “Immediate Postextraction Implant Placement with Root-Analog Stepped Implants: Surgical Procedure and Statistical Outcome After 6 Years”. The International Journal of Oral and Maxillofacial Implants 16 (2001): 503-513.
  18. Warkentin R. “Immediate tooth replacement: Strategies for success”. International Journal of Oral Implantology and Clinical Research 1 (2010): 27-32.
  19. Berberi AN., et al. “A 5-year comparison of marginal bone level following immediate loading of single-tooth implants placed in healed alveolar ridges and extraction sockets in the maxilla”. Frontiers in Physiology 5 (2014):
  20. Hotwani K and Sharma K. “Platelet rich fibrin a novel acumen into regenerative endodontic therapy”. Restorative Dentistry and Endodontics 1 (2014): 1-6.
  21. Choukroun J., et al. “Platelet rich fibrin (PRF): a second-generation platelet concentrate. Part V: histologic evaluations of PRF effects on bone allograft maturation in sinus lift”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology3 (2006): 299-303.
  22. Mazumdar P., et al. “Treatment of Periapical Lesion with Platelet Rich Fibrin”. Indian Medical Gazette (2013): 28-33.
  23. Preeja., et al. “Platelet-rich fibrin: Its role in periodontal regeneration”. The Saudi Journal Fordental Research 5 (2014): 117-122.
  24. Dohan Ehrenfest DM., et al. “Classification of platelet concentrates: From pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF)”. Trends in Biotechnology 27 (2009): 158-167. 
  25. Dohan DM., et al. “Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet related biologic features”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 3 (2016): 45-50.
  26. Dohan DM., et al. “Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part III: leucocyte activation: a new feature for platelet concentrates?” Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 101 (2006): 51-55.
  27. Sharma A and Pradeep AR. “Treatment of 3-wall intrabony defects in patients with chronic periodontitis with autologous plateletrich fibrin: a randomized controlled clinical trial”. Journal of Periodontology 82 (2011): 1705-1712.
  28. Thorat M., et al. “Clinical effect of autologous platelet-rich fibrin in the treatment of intra-bony defects: a controlled clinical trial”. Journal of Clinical Periodontology 10 (2011): 925-932.
  29. Corso MD., et al. “The Use of Leukocyte- and Platelet-Rich Fibrin During Immediate Postextractive Implantation and Loading for the Esthetic Replacement of a Fractured Maxillary Central Incisor”. Journal of Oral Implantology 2 (2012): 181-187.
  30. Dohan Ehrenfest DM., et al. “Slow release of growth factors and thrombospondin-1 in Choukroun’s platelet-rich fibrin (PRF): a gold standard to achieve for all surgical platelet concentrates technologies”. Growth Factors 27 (2009): 63-69.
  31. Moojen DJ., et al. “Antimicrobial activity of platelet-leukocyte gel against Staphylococcus aureus”. Journal of Orthopaedic Research 26 (2008): 404-410.
  32. Anitua E., et al. “Autologous platelets as a source of proteins for healing and tissue regeneration”. Journal of Thrombosis and Haemostasis 91 (2004): 4-15.
  33. Sharma A and Pradeep AR. “Autologous platelet-rich fibrin in the treatment of mandibular degree II furcation defects: a randomized clinical trial”. Journal of Periodontology 82 (2011): 1396-1403.
  34. Mazor Z., et al. “Sinus floor augmentation with simultaneous implant placement using Choukroun’s platelet-rich fibrin as the sole grafting material: a radiologic and histologic study at 6 months”. Journal of Periodontology 80 (2009): 2056-2064.
  35. Gassling V., et al. “Platelet-rich fibrin membranes as scaffolds for periosteal tissue engineering”. Clinical Oral Implants Research 21 (2010): 543-549.
  36. Singh A., et al. “Immediate placement of implant in fresh extraction socket with early loading”. Contemporary Clinical Dentistry 3 (2012): 219-222.

Citation

Citation: S Rakesh Kumar., et al. “Evaluation of Effect of PRF on Rebound of Soft Tissue in Immediate Placement of Implants-A Randomized Control Study".Acta Scientific Dental Sciences 6.8 (2022): 101-112.

Copyright

Copyright: © 2022 S Rakesh Kumar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.278

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is June 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US