Acta Scientific Dental Sciences (ASDS)(ISSN: 2581-4893)

Research Article Volume 6 Issue 7

Comparison of Effectiveness of Curcumin and Triamcinolone Acetonide in Treatment of Minor Recurrent Aphthous Stomatitis” - A Randomized Controlled Trial

Sikha Poudyal* and Anuradha Pai

Department of Oral Medicine and Radiology, The Oxford Dental College, Bangalore, India

*Corresponding Author: Sikha Poudyal, Department of Oral Medicine and Radiology, The Oxford Dental College, Bangalore, India.

Received: May 09, 2022; Published: June 20, 2022

Abstract

Background: Recurrent aphthous stomatitis is one of the most common oral mucosal condition and the manifestation of this disease can vary from mild to severe where it can even hinder a person’s ability to ingest foods, and affect their quality of life. The exact etiopathogenesis of the disease remains obscure and is not yet very clear. There is no definite curative therapy available because of its multifactorial etiology. The currently available treatment modalities aim towards shortening the duration of ulcer, provide relief from pain, and increase disease-free periods.

Aims and Objectives: The aim of the study was to evaluate the efficacy of curcumin in the treatment of minor recurrent aphthous stomatitis and the efficacy of Triamcinolone acetonide in the treatment of minor recurrent aphthous stomatitis. The objective of the study was to compare the efficacy of curcumin with triamcinolone acetonide in the treatment of minor recurrent aphthous stomatitis.

Materials and Method: 60 patients diagnosed to have minor recurrent aphthous ulcers were recruited for the study and were randomly divided into Group 1 (Curenext gel group -30) and Group 2 (Trioplast gel group - 30). The base line parameters included the size of ulcer, pain score and degree of erythema. They were recorded on the day of the first visit. On day 3 day 5 and day 7 the reduction in size of ulcer, pain and erythema was evaluated.

Results: There was marked improvement noted in both the groups with regard to the size of ulcer, pain and erythema between baseline and day 3, baseline and day 5, baseline and day 7 and day 3 and day 5 and day7. Both group 1 and group 2 were found to be effective in providing relief to the patients by reducing the size of the ulcer, pain and erythema. However when Curcumin gel group was compared with Trioplast gel group it showed significant reduction in ulcer size, pain score and degree of erythema. (P =< 0.001).

Conclusion: The results of the study suggest that both treatment groups were found to be effective in healing of ulcers, reducing the pain and erythema. The treatment of recurrent aphthous stomatitis by group 1 showed significant improvement when compared to group 2 in ulcer size, pain score and erythema proving it to be more beneficial in the treatment of minor RAS.

Keywords: Curcumin; Trioplast; Efficacy; RAS

References

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Citation

Citation: Sikha Poudyal and Anuradha Pai. “Comparison of Effectiveness of Curcumin and Triamcinolone Acetonide in Treatment of Minor Recurrent Aphthous Stomatitis” - A Randomized Controlled Trial". Acta Scientific Dental Sciences 6.7 (2022): 106-116.

Copyright

Copyright: © 2022 Sikha Poudyal and Anuradha Pai. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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