Acta Scientific Dental Sciences (ASDS)(ISSN: 2581-4893)

Research Article Volume 6 Issue 6

Identification and Frequency of Causative Organism in Oral Candidiasis in Early Childhood in Bangladesh

Ayrin Parvin1, Dipa Roy2, Nur-E-Saud3, Abdul Awal4, Md Salah Uddin5 and Ariful Haque2*

1Dental Pharmacology, Dental Unit, Rajshahi Medical College, Rajshahi, Bangladesh
2Molecular Pathology Laboratory, Institute of Biological Sciences, University of Rajshahi, Rajshahi, Bangladesh
3Science of Dental Material and Engineering, Dental Unit, Rajshahi Medical College, Rajshahi, Bangladesh
4Department of Public Health, Varendra University, Rajshahi, Bangladesh.
5Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi, Bangladesh

*Corresponding Author: Ariful Haque, Molecular Pathology Laboratory, Institute of Biological Sciences, University of Rajshahi, Rajshahi, Bangladesh.

Received: April 19, 2022; Published:


Introduction: Opportunistic infections may be caused by the part of the normal flora in the oral cavity called Candidiasis. This may happen in different circumstances and might be a matter of serious concern by comprising the host immunity in addition to augmented resistance to antifungal drugs. The study was aimed at using various clinical samples for appraising utility of HiCrome Candida Differential Agar to differentiate Candida species isolated. This is to be done on the basis of coloration and colony morphology. The study was conducted with an aim to establish a preliminary picture of the different Candida species causing oral candidiasis of the children by defining the existence and the influencing circumstances of the needs of community-based treatment for oral candidiasis.

Methodology: The study was conducted over a period of two year (January 2018 to December 2019) by collecting 148 number of Candida isolates from oral mucosa and tongue. The samples were being collected from the Dental Unit at Rajshahi Medical College Hospital outdoor which was further examined at the Molecular Pathology Laboratory of the Institute of Biological Sciences, University of Rajshahi. The use of chromogenic agar medium (HiCrome Candida differential agar) speciated the Candida isolates.

Result: Total 148 respondents, 23 of them were less than 1 year of age, 112 of them were between 1-3 years and 13 of them were between 4-6 years of old. The isolation of Candida albicans 140 (94.5%) predominated over non albicans Candida. Non albicans Candida species isolated were Candida tropicalis 108 (72.9%) followed by Candida krusei 68 (45.9%) and Candida parapsilosis 36 (24.3%).

Conclusion: As a convenient and rapid method of identification of Candida species HiCrome Candida differential agar is considered. Candida albicans was the major species isolated in the conducted study and children aged 1-3 year are most susceptible to recurrent oral candidiasis in the study. In choosing the proper antifungal agents, the sensitivity profile of Candida isolates is to be helpful as it may decrease the morbidity and mortality of the patients.

Keywords: Oral Candidiasis; Candida Albicans; HiCrome Candida Differential Agar; Antifungal Susceptibility Test; Minimum Inhibitory Concentration


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Citation: Ariful Haque., et al. “Identification and Frequency of Causative Organism in Oral Candidiasis in Early Childhood in Bangladesh". Acta Scientific Dental Sciences 6.6 (2022): 00-00.


Copyright: © 2022 Ariful Haque., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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