B Cells in Periodontitis - A Friend or Foe?
Dr. Bhalchandra Bhausaheb Thorat*, Dr. Mala Dixit Baburaj, Pradnya Dattatraya Kadam and Sandeep K Pmiple
Department of Periodontics, Nair Hospital and Dental College, India
*Corresponding Author: Dr. Bhalchandra Bhausaheb Thorat, Department of
Periodontics, Nair Hospital and Dental College, India.
Received: April 05, 2022; Published: April 26, 2022
It is evident that B lymphocytes and Plasma cells superior among cells in periodontitis. Despite the fact that T cells work as the principal regulatory group of cells, B cells seem to have several critical roles in periodontitis. The capacity of B cells to demonstrate class II antigens and contribute to antigen presentation has been revealed in periodontal diseases. Different subtypes of B cells, such as B-1a and B-2 cells are present in periodontal lesions. Increased level of B-1a cells has been reported in subjects with severe forms of periodontitis. B-1a cells have been associated with interleukin-10 and this cytokine serves as an autocrine growth factor for this type of B cell. Despite the fact that microbial antigens are associated with the initiation of the inflammatory responses in periodontitis, endogenous antigens also play a part in the chronicity of periodontal disease.
Keywords: Periodontitis; B Cells; T Cells; Bone Loss
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