Bone Grafts – A Valuable Substitute for Replacing Bony Defects- A Review
Pradeep C Dathan1, Deepak Nallaswamy2, S Rajeshkumar3, Suja
Joseph14, Shahin Ismail5 and K Chandrasekharan Nair6*
1Professor and Head of the Department of Prosthodontics, Sri Sankara Dental
College, Akathumuri, Thiruvavananthapuram, Kerala, India
2Director, Department of Prosthodontics, Saveetha Dental College, Chennai, India
3Chief Scientist, Nanobiomedicine Lab, Dept. of Pharmacology, Saveetha Dental College, Chennai, India
4Professor, Department of Prosthodontics, Pushpagiri College of Dental Sciences, Thiruvalla, Kerala, India
5Reader, Department of Prosthodontics, Sri Sankara Dental College, Akathumuri, Thiruvavananthapuram, Kerala, India
6Professor Emeritus, Department of Prosthodontics, Sri Sankara Dental College, Akathumuri, Thiruvavananthapuram, Kerala, India
*Corresponding Author: K Chandrasekharan Nair, Professor Emeritus, Department of Prosthodontics, Sri Sankara Dental College, Akathumuri, Thiruvavananthapuram, Kerala, India.
Received: March 04, 2022; Published: March 15, 2022
Abstract
Numerous graft materials are in use of which autografts are considered as a gold standard. Autografts have the uniqueness of having osteogenic, osteoinductive and osteoconductive potential. At the same time, they have well identified disadvantages too which include donor site morbidity, graft availability and the risk of disease transmission. Synthetic graft substitutes do not have osteoinductive or osteogenic properties. Composite grafts are also being used effectively for osteogenesis. The limited availability of suitable bone grafts has ushered in the era of tissue engineering for bone repair. Additive manufacturing, also known as 3D printing, is considered as an ideal method for orthopedic applications such as bone grafting. Here in this review the scope of bone grafts and graft substitutes used for different clinical applications is discussed.
Keywords: Bone Graft; Bone Graft Substitute; Autografts; Allografts; Xenografts; Alloplast; Mesenchymal Cells
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