Acta Scientific Dental Sciences (ISSN: 2581-4893)

Research ArticleVolume 5 Issue 5

Diabetomics- A Potential Saliva Based Diabetes Diagnosis

Prerana G1, Aishwarya P R Kumar1 and Gaurav2*

1House Surgeons, NSVK Sri Venkateshwara Dental College and Hospital, Bangalore, Karnataka, India
2Consultant Oral Physician and Maxillofacial Radiologist, Assistant Professor, Department of Oral Medicine and Maxillofacial Radiology, NSVK Sri Venkateshwara Dental College and Hospital, Bangalore, Karnataka, India

*Corresponding Author: Gaurav, Consultant Oral Physician and Maxillofacial Radiologist, Assistant Professor, Department of Oral Medicine and Maxillofacial Radiology, NSVK Sri Venkateshwara Dental College and Hospital, Bangalore, Karnataka, India.

Received: May 08, 2021; Published: : May 21, 2021

Citation: Gaurav., et al. “Diabetomics- A Potential Saliva Based Diabetes Diagnosis". Acta Scientific Dental Sciences 5.6 (2021): 98-103.

Abstract

Background: With 400 million individuals suffering from one of the most prevalent conditions known to mankind diabetes; there still exists an age old invasive diagnostic and self-assessment criteria which is till date considered to be the gold standard. Everyday approximately 0.4 - 2.8 litres of saliva is produced within the oral cavity; which raises a question as to why we cannot use this human serum to diagnose diabetes. The abundance of biomarkers such as genetic material and protein it contains, it is hard to ignore this as a beginning of a new era of using saliva as a potent non-invasive diagnostic tool.

Aim of the Study: To assess the significance of salivary proteins in diagnosis of Type 2 Diabetes (Insulin Independent Diabetes Mellitus).

Research Question: Is Diabetomics actually significant enough in diagnosing Type 2 Diabetes (Insulin Independent Diabetes Mellitus).

Materials and Methods: With the Medline database taken as a source for authenticated scientific research data including few others like Cochrane and Medknow, 55 articles were selected having undergone Randomized Control Trial (RCT). Out of these, 19 articles (studies) were chosen which met the inclusion and exclusion criterion for systematic review.

Results and Conclusion: The conventional methods of diagnosis have a lot of demerits associated with it. Diabetomics on the other hand, can be used as a potential diagnostic tool in the diagnosis of Diabetes Mellitus Type 2. Saliva being a complex fluid with its constituents similar to that of plasma can be unmistakably devoted to the field of diagnosis. Not only can it serve as a diagnostic aid for Diabetes, if the salivary biomarkers are utilized to its full potential, it can be used for the diagnosis of a plethora of diseases [1].

 

Keywords: Diabetes Mellitus; Diabetomics; Type 2 Diabetes

Bibliography

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    2. Ladgotra Amit., et al. “Estimation of Salivary and Serum Biomarkers in Diabetic and Non Diabetic Patients - A Comparative Study”. Journal of Clinical and Diagnostic Research: JCDR6 (2016): ZC56-61.
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    8. Agho Ekhosuehi Theophilus., et al. “Salivary inflammatory biomarkers and glycated haemoglobin among patients with type 2 diabetic mellitus”. BMC Oral Health1 (2021): 101.
    9. Caixeta Douglas C., et al. “Salivary molecular spectroscopy: A sustainable, rapid and non-invasive monitoring tool for diabetes mellitus during insulin treatment”. PloS one3 (2020): e0223461.
    10. Guo Lin-Na., et al. “Serum and salivary ferritin and Hepcidin levels in patients with chronic periodontitis and type 2 diabetes mellitus”. BMC Oral Health1 (2018): 63.
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    Copyright: © 2021 Gaurav., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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