Acta Scientific Dental Sciences (ISSN: 2581-4893)

Research Article Volume 5 Issue 3

A Comparison between the Antibacterial Activity of Propolis and Ginseng Extracts on Porphyromonas gingivalis and Prevotella intermedia Isolated from Patients with Chronic Periodontitis

Heba A Shawky1 and Walid A Lotfy2*

1Associate Professor of Periodontics, Preventive Dental Science Department, College of Dentistry, Princess Nourah Bint Abdulrahman University, Kingdom of Saudi Arabia
2Microbiology Department, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt

*Corresponding Author: Walid A Lotfy, Microbiology Department, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.

Received: June 05, 2020; Published: February 16, 2021



  The antimicrobial activity of ginseng extract was investigated in-vitro against 24 clinical isolates of Porphyromonas gingivalis and Prevotella intermedia. To our knowledge, there is a lack of researches on the evaluation of the antimicrobial effectiveness of ginseng extract on periodontopathic bacteria. We also compared the in-vitro antibacterial action of ginseng extract to that of propolis extract by agar diffusion method. The MIC values of ginseng extract against Porphyromonas gingivalis and Prevotella intermedia were 512 and 1024 mg/ml, respectively. While the MIC obtained for propolis extract were 256 and 512 mg/ml against Porphyromonas gingivalis and Prevotella intermedia, respectively. Moreover, the statistical analysis for the effect of ginseng and propolis extracts on Porphyromonas gingivalis and Prevotella intermedia using student paired t-test revealed a significant difference between the two groups (p < 0.001). However, the anti-Porphyromonas gingivalis and anti-Prevotella intermedia mean activities of ginseng extract were lower than that of propolis extract by 1.32 and 0.17 AU, respectively. The results of the current study support the usage of ginseng extract as an adjuvant to periodontal therapy after proper in-vivo studies are performed.

Keywords: Prevotella intermedia; Porphyromonas gingivalis; Propolis Extract; Ginseng Extract; Antibacterial



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Citation: Heba A Shawky and Walid A Lotfy. “A Comparison between the Antibacterial Activity of Propolis and Ginseng Extracts on Porphyromonas gingivalis and Prevotella intermedia Isolated from Patients with Chronic Periodontitis". Acta Scientific Dental Sciences 5.3 (2021): 82-87.


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