Acta Scientific Dental Sciences (ISSN: 2581-4893)

Review Article Volume 4 Issue 11

PRF from the Perspective of a Daily Practitioner: Where are the Limits?

Andreas Van Orten1 and Hakan Bilhan2*

1Private Dental Practice, Waltrop, Germany
2Witten/Herdecke University, School for Health Sciences, Department of Periodontology, Germany

*Corresponding Author: Hakan Bilhan, Witten/Herdecke University, School for Health Sciences, Department of Periodontology, Germany.

Received: September 23, 2020; Published: October 28, 2020



Background: Platelet-rich fibrin (PRF) is being used in dentistry as an over physiological concentrate of autologous growth factors capable of stimulating tissue regeneration and being increasingly more popular in private practice. Since about 20 years platelet concentrates are being used in oral and maxillofacial surgery. With various modifications, mainly concerning the presence or absence of leukocytes and their concentration, as well as the presence and consistency of the fibrin matrix, the scope of application has continuously expanded.

Methods: The range of developments and studies on PRF is extensive. On the one hand, technical aspects such as centrifuge speed, forces and duration, on the other hand medical factors such as influence of the individual donor on fibrin product, or the hematocrit or the count of erythrocytes on the fibrin matrix or aspects of the further processing of the fibrin matrices, for example by heat application, to slow down degradation, so that the PRF membrane could become comparable to collagen membranes, are studied.

Primary Results: An international effort to extend the application diversity can be observed, as well.

Principal Conclusions: In future, it can be expected that PRF will be a precious addition in maxillofacial surgery and also in the treatment of temporomandibular joint diseases, endodontics (pulp regeneration), the regeneration of peri-implant soft tissues around implants, the modification of the lip volume, to name a few.

Keywords: Platelet-rich Fibrin; Regeneration; Growth Factors; Improved Healing; Autologous



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Citation: Andreas Van Orten and Hakan Bilhan. “PRF from the Perspective of a Daily Practitioner: Where are the Limits?". Acta Scientific Dental Sciences 4.11 (2020): 54-59.


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