Acta Scientific Dental Sciences (ISSN: 2581-4893)

Review Article Volume 4 Issue 8

Role of Human Papilloma Virus (HPV) in Potentially Malignant and Malignant Lesions of Head and Neck

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Paramita Ingle1*, Basavaraj Bhagawati2 and Meenal Jethlia1*

1Post Graduate Student, Department of Oral Medicine and Radiology, Saraswati Dhanvantari Dental College and Hospital, Parbhani, Maharashtra, India
2Professor and Head, Department of Oral Medicine and Radiology, Saraswati Dhanvantari Dental College and Hospital, Parbhani, Maharashtra, India

*Corresponding Author: Paramita Ingle, Post Graduate Student, Department of Oral Medicine and Radiology, Saraswati Dhanvantari Dental College and Hospital, Parbhani, Maharashtra, India.

Received: July 04, 2020; Published: July 27, 2020

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Abstract

The sixth most common cancer diagnosed worldwide are head and neck cancer (HNC). In 2008, 633,000 new cases were diagnosed out of which 355,000 cases resulted in mortality. Early detection of precancerous lesions remains a challenge to clinicians. In 1983, evidence of Human Papilloma Virus (HPV) infection was identified in a subset of oropharyngeal carcinomas (OPC). Thus, confirming HPV as a causative agent in HNC. HPV is now recognized as an important risk factor for the development of oropharyngeal cancers, and results of previous studies have demonstrated epidemiological and molecular evidence of the presence of the HPV genome in pre-malignant oral lesions in SCC tissues, especially of the subtypes of HPV-16 and -18. There is close to no evidence linking HPV to carcinoma. However, this review focuses on the role of HPV in oral oncology and to comment on the HPV DNA reported frequencies potentially malignant oral lesions.

Keywords: Human Papilloma Virus (HPV); Malignant Lesion; Malignancy

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References

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Citation

Citation: Paramita Ingle., et al. “Role of Human Papilloma Virus (HPV) in Potentially Malignant and Malignant Lesions of Head and Neck".Acta Scientific Dental Sciences 4.8 (2020): 52-57.




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