Acta Scientific Dental Sciences (ISSN: 2581-4893)

Review Article Volume 4 Issue 3

Role of Steroids in Oral Mucosal Lesions: A Review

Shriya Khera1 and Sunita Gupta2*

1Senior Resident, Department of Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, India
2Professor and Head, Department of Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, India

*Corresponding Author: Sunita Gupta, Professor and Head, Department of Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, India

Received: February 04, 2020; Published: February 26, 2020

×

Abstract

  From the advent of steroids, they have been an elixir for various diseases. The medicinal benefit of the steroids is due to their anti inflammatory and immunosuppressive properties which are beneficial for the treatment of various oral mucosal lesions. This review article is aimed at understanding the various types of steroids, their chemical structure, the review of various concentrations of steroids used and their effects.

Keywords: Steroids; Oral Mucosal Lesions

×

References

  1. Sweetman SC., et al. “Martindale, The Complete Drug Reference”. Pharmaceutical Press, 37th edition (2011).
  2. Moss GP. “IUPAC-IUB Joint Commission on Biochemical Nomenclature (JCBN), The nomenclature of steroids. Recommendations”. European Journal of Biochemistry 186 (1989): 429-458.
  3. The Great Soviet Encylopedia, 3rd Edition 1970-1979.
  4. Thompson AC., et al. “Minor aphthous oral ulceration: a double-blind cross-over study of beclomethasone dipropionate aerosol spray”. Scottish Medical Journal 34 (1989): 531-532.
  5. Vincent SD and Lilly GE. “Clinical, historic, and therapeutic features of aphthous stomatitis. Literature review and open clinical trial employing steroids”. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology 74 (1992): 79-86.
  6. Voûte AB., et al. “Fluocinonide in an adhesive base for treatment of oral lichen planus. A double-blind, placebo-controlled clinical study”. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology 75.2 (1993): 181-185.
  7. Cribier B., et al. “Treatment of lichen planus. An evidence-based medicine analysis of efficacy”. Archives of Dermatology 134.12 (1998): 1521-1530.
  8. Lodi G., et al. “Current controversies in oral lichen planus: report of an international consensus meeting. Part 2. Clinical management and malignant transformation”. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology 100.2 (2005): 164-178.
  9. Rabiyi M and Sahebjamee M. “Effect of aqueous triamcinolone actonide 0.2% suspension in treatment of oral lichen planus”. Journal Medical Faculty Guilan University of Medical Sciences 12 (2003): 6-14.  
  10. Thongprasom K., et al. “Clinical evaluation in treatment of oral lichen planus with topical fluocinolone acetonide: a 2year follow-up”. Journal of Oral Pathology and Medicine 32 (2003): 315-322. 
  11. Buajeeb W., et al. “Efficacy of fluocinolone acetonide gel in the treatment of oral lichen planus”. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology 89 (2000): 42-45. 
  12. Carbone M., et al. “The topical treatment of atrophic-erosive oral lichen planus with fluocinolone in a bioadhesive gel, chlorhexidine, and miconazole gel. A totally open trial [Italian]”. Minerva Stomatol. 45 (1996): 61-68.
  13. McGrath C., et al. “Patient-centred outcome measures for oral mucosal disease are sensitive to treatment”. International Journal of Oral and Maxillofacial Surgery 32 (2003): 334-336.
  14. Holbrook WP., et al. “Aqueous hydrocortisone mouthwash solution: clinical evaluation”. Acta Odontologica Scandinavica 56 (1998): 157-160. 
  15. Hegarty AM., et al. “Fluticasone propionate spray and betamethasone sodium phosphate mouthrinse: a randomized crossover study for the treatment of symptomatic oral lichen planus”. Journal of the American Academy of Dermatology 47 (2002): 271-279. 
  16. Aguirre JM., et al. “Efficacy of mometasone furoate microemulsion in the treatment of erosive-ulcerative oral lichen planus: pilot study”. Journal of Oral Pathology and Medicine 33 (2004): 381-385.
  17. Sardella A., et al. “Efficacy of topical mesalazine compare with clobetasol propionate in treatment of symptomatic oral lichen planus”. Oral Diseases 4 (1998):  255259. 
  18. Lo Muzio L., et al. “The treatment of oral aphthous ulceration or erosive lichen planus with topical clobetasol propionate in three preparations: a clinical and pilot study on 54 patients”. Journal of Oral Pathology and Medicine 30 (2001): 611-617. 
  19. Gonzalez-Moles MA., et al. “Treatment of severe chronic oral erosive lesions with clobetasol propionate in aqueous solution”. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology 93 (2002): 264-270.
  20. Gonzalez-Moles MA., et al. “Treatment of severe erosive gingival lesions by topical application of clobetasol propionate in custom trays”. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology 95 (2003): 688-692.
  21. Conrotto D., et al. “Ciclosporin vs. clobetasol in the topical management of atrophic and erosive oral lichen planus: a doubleblind, randomized controlled trial”. British Journal of Dermatology 154 (2006):139-114.
  22. Ungphaiboon S., et al. “Formulation and efficacy of triamcinolone acetonide mouthwash for treating oral lichen planus”. American Journal of Health-System Pharmacy 62 (2005): 485491. 
  23. Xia J., et al. “Short-term clinical evaluation of intralesional triamcinolone acetonide injection for ulcerative oral lichen planus”. Journal of Oral Pathology and Medicine 35 (2006): 327-331.
  24. Laeijendecker R., et al. “A comparison of treatment of oral lichen planus with topical tacrolimus and triamcinolone acetonide ointment”. Acta Dermato-Venereologica 86 (2006): 227-229.
  25. Thongprasom K., et al. “Clinical evaluation in treatment of oral lichen planus with topical fluocinolone acetonide: a 2-year follow-up”. Journal of Oral Pathology and Medicine 32 (2003): 315-322.
  26. Almugairen N., et al. “Assessment of the rate of long-term complete remission off therapy in patients with pemphigus treated with different regimens including medium- and high-dose corticosteroids”. Journal of the American Academy of Dermatology 69.4 (2013): 583-588. 
  27. Hertl M., et al. “Pemphigus. S2 guideline for diagnosis and treatment – guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV)”. Journal of the European Academy of Dermatology and Venereology 29 (2015): 405-414.
  28. Ratnam KV., et al. “Pemphigus therapy with oral prednisolone regimens: a 5-year study”. International Journal of Dermatology 29 (1990): 363-367.
  29. Harman KE., et al. “British Association of Dermatologists. Guidelines for the management of pemphigus vulgaris”. British Journal of Dermatology 149 (2003): 926-937.
  30. Atzmony L., et al. “The role of adjuvant therapy in pemphigus: a systematic review and meta-analysis”. Journal of the American Academy of Dermatology 73.2 (2015): 264-271.
  31. James L., et al. “Management of oral submucous fibrosis with injection of hyaluronidase and dexamethasone in Grade III oral submucous fibrosis: A retrospective study”. Journal of International Oral Health 7.8 (2015): 82-85.
  32. Le PV., et al. “Oral stent as treatment adjunct for oral submucous fibrosis”. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology 81.2 (1996): 148-150.
  33. Chole RH., et al. “Review of drug treatment of oral submucous fibrosis”. Oral Oncology 48.5 (2012): 393-398.
  34. Robert A Lindemann., et al. “Serum antibody response to indigenous oral mucosal antigens and selected laboratory-maintained bacteria in Recurrent Apthous ulcerations”. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology 59 (1985): 585-589.
  35. S Jurge., et al. “Recurrent Apthous Stomatitis”. Oral Diseases 12 (2006): 1-21.
  36. Crispian scully and Stephen Porter. “Oral Mucosal Diseases: Recurrent Apthous Stomatitis”. British Journal of Oral and maxillofacial Surgery 46 (2008): 198-206.
  37. Crispian scully., et al. “Aphthous Ulcerations”. Dermatologic Therapy 15 (2002): 185-205.
  38. IT Macphee., et al. “Use of Steroids in Treatment of Aphthous Ulceration”. British Medical Journal 2 (1968): 147-114.
×

Citation

Citation: Shriya Khera and Sunita Gupta. “Role of Steroids in Oral Mucosal Lesions: A Review”. Acta Scientific Dental Sciences 4.3 (2020): 99-104.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.278

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is December 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"

Contact US









ff

© 2024 Acta Scientific, All rights reserved.