Abstract

  Metastasis is the leading cause of fatality in 90% of cancers, and approximately 60% of all cancer cases will have either regional or distant metastasis at initial diagnosis. Global data shows that survival rates drop significantly with the advance of disease stage and metastatic activity; therefore, patients with localised disease have a far better prognosis than those with disseminated tumours. In this aspect, oral squamous-cell carcinoma (OSCC) is locally invasive neoplasms. Both cancers are considered the worst prognosis cancers with an overall survival rate of 50% or slightly higher. In this review, we summarise the latest data in the literature about the impact of metastasis on oral cancer prognosis and the choice of treatment, emphasising the urgent need for reliable markers for the early detection and prevention of oral neoplasms to improve the patient outcome.

Keywords: Metastasis; Oral Squamous Cell Carcinoma; Oral Cancer; Prognosis; Treatment

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Citation

Citation: Moustafa Elhousiny. “The Effect of Metastasis on Treatment and Prognosis of Oral Cancer: Short Review".Acta Scientific Dental Sciences 4.1 (2020): 111-116.

Copyright

Copyright: © 2020 Moustafa Elhousiny. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.