YI Karachentsev 2,NA Kravchun1, OV Zemlianitsyna2, IP Dunaieva1*, IV Cherniavskaya1 and OM Bilovol1
1Kharkiv National Medical University, Kharkiv, Ukraine
2State Institution “V. Danilevsky Institute for Endocrine Pathology Problems of the National Academy of Medical Sciences of Ukraine”, Kharkiv, Ukraine
*Corresponding Author: IP Dunaieva, Kharkiv National Medical University, Kharkiv, Ukraine.
Received: October 14, 2022; Published: October 25, 2022
The necessity of determining and assessing the dynamics of albuminuria and glomerular filtration rate in patients with type 1 and type 2 DM (as an early marker of endothelial dysfunction and a predictor of cardiovascular complications) was substantiated amid pathogenetic therapy with glycosaminoglycan sulodexide. There is a clinically significant decrease in the levels of both total protein and albumin in the urine, which along with an increase in glomerular filtration rate indicates an improvement in renal microcirculation. It is worth pointing out that the increase in glomerular filtration rate is mostly evident among type 2 DM patients with comorbid non-alcoholic fatty liver disease.
Keywords: Diabetes Mellitus; Albuminuria; Endothelial Dysfunction; Non-alcoholic Fatty Liver Disease; Treatment
Citation: IP Dunaieva., et al. “Albuminuria as an Independent Factor of Cardiovascular Complications in Patients with Comorbid Pathology". Acta Scientific Cardiovascular System 1.6 (2022): 02-09.
Copyright: © 2022 IP Dunaieva., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.