Abstract

Background: Structural changes in the myocardium damage the antioxidant barrier of the cardiac conduction pathways, which contributes to the rapid oxidation of one or more ectopic nodes with the development of paroxysmal tachyarrhythmias. To evaluate the effectiveness of the complex treatment of paroxysmal atrial fibrillation and flutter (AF and TP), in comparison with monotherapy of an antiarrhythmic drug of the IC class - propanorm.

Methods: The study involved 63 patients with the first-occurring paroxysmal form of atrial fibrillation and flutter. Patients in the control group underwent standard therapy (propanorm, dabigatran), the study group used complex treatment (propanorm, sodium bicarbonate, Kudesan Q10, solcoseryl, dabigatran).

Results: The study showed; the combined therapeutic effect on the mechanism of atrial fibrillation and flutter with the structural pathology of the atria leads to a significant effect, in comparison with only one antiarrhythmic drug.

Conclusion: This effect is achieved due to additional antioxidant therapy with sodium bicarbonate and Kudesan (Q10), as well as the repository - solcoseryl.

Keywords: Flutter; Atrial Fibrillation; Reparants; Antioxidant Drugs

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Citation

Citation: Rustam G Khabchabov and Elmira R Makhmudova. “Paroxysmal Atrial Fibrillation, Combined Treatment Taking into Account the Correction of Myocardial Oxidative Stress". Acta Scientific Cardiovascular System 1.5 (2022): 19-25.

Copyright

Copyright: © 2022 Rustam G Khabchabov and Elmira R Makhmudova. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.