An Uncommon Presentation of a Common Disease - Dengue Presenting as Hemorrhagic Acute Disseminated Encephalomyelitisy
Pranav Ish1, Arjun Bhatnagar2, Neha Tripathi3 and Himanshu Sharma4*
1Assistant Professor, Department of Pulmonary, Critical care and Sleep Medicine, VMMC and Safdarjung Hospital, New Delhi, India
2Senior Resident, Department of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New Delhi, India
3Consultant IVF Specialist, Indira IVF, Rajnagar, Ghaziabad, Uttar Pradesh, India
4Assistant Professor, Department of Endocrinology, Rajiv Gandhi Super Speciality Hospital, Tahirpur, New Delhi, India
*Corresponding Author: Himanshu Sharma, Assistant Professor, Department of Endocrinology, Rajiv Gandhi Super Speciality Hospital, Tahirpur, New Delhi, India.
Received:
October 29, 2021; Published: December 10, 2021
Abstract
Dengue fever is a major seasonal health care problem in the tropics and the developing countries like India affecting thousands of patients every year. The common presentations include fever, myalgia, arthralgia and sometimes shock and bleeding manifestations. Acute disseminated encephalomyelitis (ADEM) complicating dengue infection is rare even in endemic countries such as India. We report a case of dengue fever presenting as ADEM.
Keywords: Dengue; Mosquito; Acute Disseminated Encephalomyelitis (ADEM)
References
- Halstead SB. “Dengue”. Lancet 370 (2007): 1644-1652.
- Mustafa MS., et al. “Discovery of fifth serotype of dengue virus (DENV-5): a new public health dilemma in dengue control”. Medical Journal of Armed Forces India 71 (2015): 67-70.
- Dengue W. “Guidelines for Diagnosis, Treatment. Prevention and Control” Geneva. World Health Organization (2009).
- Srinivasa Rao Mutheneni., et al. “Dengue burden in India: recent trends and importance of climatic parameters”. Emerging Microbes and Infections8 (2017): e70.
- “Dengue cases and deaths in India since 2015” (2018).
- Carod-Artal., et al. “Neurological complications of dengue virus infection”. Lancet Neurology9 (2013): 906-919.
- Domingues RB and Kuster GW. “Diagnosis and management of neurologic manifestations associated with acute dengue virus infection”. Journal of Neuroinfectious Diseases 5 (2014): 138.
- Gupta M., et al. “Acute disseminated encephalomyelitis associated with dengue infection: a case report with literature review”. Journal of the Neurological Sciences1-2 (2003): 216-218.
- Mudin NR. “Dengue incidence and the prevention and control program in Malaysia”. International Medical Journal Malaysia1 (2015): 5-9.
- Puccioni-Sohler M., et al. “Dengue: a new challenge for neurology”. Neurology International3 (2012): e15.
- Pancharoen C., et al. “Dengue infection: a global concern”. Journal of the Medical Association of Thailand 85 (2002): S25-S33.
- Puccioni-Sohler., et al. “Neurological complications in dengue infection: a review for clinical practice”. Arquivos de Neuro-Psiquiatria9-B (2013): 667-671.
- Ascherio A and Munger K. “Epidemiology of multiple sclerosis: From risk factors to prevention”. Seminars in Neurology 28 (2008): 17-28.
- Panicker JN. “Acute Disseminated Encephalomyelitis”. Clinical Profile and Predictors of Outcome (Dissertation). Bangalore: National Institute of Mental Health and Neurosciences, NIMHANS (Deemed University) (2004).
- Menge T., et al. “Acute disseminated encephalomyelitis: An update”. Archives of neurology 62 (2005): 1673-1680.
- Anlar B., et al. “Acute disseminated encephalomyelitis in children: Outcome and prognosis”. Neuropediatrics 34 (2003): 194-199.
- Tenembaum S., et al. “Acute disseminated encephalomyelitis: A long-term follow-up study of 84 pediatric patients”. Neurology 59 (2002): 1224-1231.
- Gera C and George U. “Acute disseminating encephalomyelitis with haemorrhage following dengue”. Neurology India 58 (2010): 595-596.
- Chowdhury RN., et al. “Dengue fever as a cause of acute disseminated encephalomyelitis (ADEM)”. Journal of Medicinal Chemistry 12 (2011): 185-187.
- Sundaram C., et al. “Acute disseminated encephalomyelitis following dengue hemorrhagic fever”. Neurology India 58 (2010): 599-601.
- Li GH., et al. “Neurological Manifestations of Dengue Infection”. Frontiers in Cellular and Infection Microbiology 7 (2017): 449.
- Verma R., et al. “Neurological complications of dengue fever: Experience from a tertiary center of north India”. Annals of Indian Academy of Neurology 4 (2011): 272-278.
- Murthy JM. “Acute disseminated encephalomyelitis”. Neurology India 50 (2002): 238-243.
- Noseworthy JH and Hartung HP. “Multiple Sclerosis and Related Conditions”. Neurological Therapeutics. Principles and Practice. (2nd Ed) 1 (2006): 1225-1250.
- Straub J., et al. “Early high-dose intravenous methylprednisolone in acute disseminated encephalomyelitis: A successful recovery”. Neurology 49 (1997): 1145-1147.
- Leake JA., et al. “Acute disseminated encephalomyelitis in childhood: epidemiologic, clinical and laboratory features”. The Pediatric Infectious Disease Journal 8 (2004): 756-764.
- Massa S., et al. “Update on Acute Disseminated Encephalomyelitis in Children and Adolescents”. Children (Basel) 8.4 (2021): 280.
- Esposito S., et al. “A spectrum of inflammation and demyelination in acute disseminated encephalomyelitis (ADEM) of children”. Autoimmunity Reviews 14 (2015): 923-929.
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