Acta Scientific Clinical Case Reports

Case Report Volume 1 Issue 11

COVID-19 Infection in Patient with Sudden Onset Anosmia in the Current Pandemic: Experience in Private Otolaryngology Practice

Md Harun Ar Rashid Talukder1*, Abul Hasnat Joarder2 and Mohammad Wahiduzzaman1

1Assistant Professor, Otolaryngology-Head and Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
2Professor, Otolaryngology-Head and Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

*Corresponding Author: Md Harun Ar Rashid Talukder, Assistant Professor, Otolaryngology-Head and Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Received: November 17, 2020; Published: November 28, 2020

×

Abstract

Background: The novel human corona virus disease (COVID-19) is the fifth documented pandemic in history since the 1918 flu pandemic. Along with other clinical features, anosmia has been reported as a prime symptom in COVID-19 positive patients. The aim is to determine the prevalence of COVID-19 infection in patients who came with a history of the sudden development of anosmia.

Methodology: This study was done in a consultation center, Uttara Crescent Hospital, a privately owned hospital in Dhaka, Bangladesh. Data were collected retrospectively from hospital records in between 01 April 2020 and 15 October 2020. Patients came with history of fever, sore throat, cough, loss of smell and altered taste, proper history were taken and examined. All the patients with suspected COVID-19 infection were sent for RT-PCR testing. Only 19 patients were included in the study with the history of anosmia from the recorded data.

Results: Among the 19 patients male were 13 and female 06. The age of the patients was in between 16 and 63 years. COVID-19 infection was confirmed in 13 patients (68.42%) in RT-PCR testing among the 19 cases.

Conclusion: Loss of smell is a significant symptom of COVID-19 infection, along with other symptoms. In the current study, the prevalence of COVID-19 infection is 68.42% in patients with history of sudden onset anosmia in Dhaka, Bangladesh. It does not reflect the country’s actual picture because of a minimal number of study populations. Further study is needed find out prevalence in Bangladesh.

Keywords: COVID-19; Anosmia; SARS-CoV-2; Corona Virus

×

References

  1. Yen-Chin Liua., et al. “COVID-19: The first documented coronavirus pandemic in history”. Biomedical Journal4 (2020): 328-333.
  2. “COVID -19 and vascular disease”. EBioMedicine (2020).
  3. Coronavirus disease 2019, From Wikipedia, the free encyvclopedia.
  4. “Novel Coronavirus – China”. World Health Organization (WHO) (2020).
  5. “Naming the coronavirus disease (COVID-19) and the virus that causes it”. World Health Organization (WHO).
  6. “Q&A on coronaviruses (COVID-19)”. World Health Organization (2020).
  7. https://www.ecdc.europa.eu/en/covid-19/facts/questions-answers-basic-facts
  8. “COVID-19: epidemiodogy, virology and clinical features”. GOV.UK (2020).
  9. Hummel T., et al. “Position paper on olfactory dysfunction”. Rhinology1 (2017): 1-30.
  10. Welge-Lüssen A. “Re-establishment of olfactory and taste functions”. GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery 4 (2005).
  11. Hummel T., et al. “Smell and taste disorders”. GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery 10 (2011).
  12. Seyed Hamid Reza Bagheri., et al. “Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak”. Medical Journal of The Islamic Republic of Iran (2020).
  13. Mao L., et al. “Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China”. JAMA Neurology6 (2020): 683-690.
  14. Jane Y Tong., et al. “The Prevalence of Olfactory and Gustatory Dysfunction in COVID-19Patients: A Systematic Review and Meta-analysis”. Otolaryngology–Head and Neck Surgery 1 (2020): 3-11.
  15. Centers for Disease Control and Prevention. “Coronavirus disease 2019 (COVID-19)—symptoms”. (2020).
  16. Isabelle Gengler., et al. “Sinonasal pathophysiology of SARS-CoV-2 and COVID-19: A systematic review of the current evidence”. Laryngoscope Investigative Otolaryngology 3 (2020): 354-359.
  17. Kevin Jiang. “How COVID-19 causes loss of smell. Harvard Medical School webpage in research section”. www.harvardmedicalschool.com
  18. Sungnak W., et al. “SARS-CoV-2 entry genes are most highly expressed in nasal goblet and ciliated cells within human airways” (2020).
  19. Prasun Mishra., et al. “Prevalence of New Onset Anosmia in COVID-19 Patients: Is The Trend Different Between European and Indian Population”. Indian Journal Otolaryngology Head Neck Surgery4 (2020): 484-487.
  20. Klopfenstein T., et al. “Features of anosmia in COVID-19”. Me´decine et Maladies Infectieuses (2020).
  21. Lechien JR., et al. “Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicentre European study”. European Archives of Otorhinolaryngology 8 (2020): 2251-2261.
  22. Quazi Tarikul Islam., et al. “Clinico-Demographic Profile, Treatment Outline and Clinical Outcome of 236 Confirmed Hospitalized COVID-19 Patients: A Multi-Centered Descriptive Study in Dhaka, Bangladesh”. Bangladesh Journal of Medicine 2 (2020): 52-57.
  23. Syed Ghulam Mogni Mowla., et al. “Clinical Profile of 100 Confirmed COVID-19 Patients Admitted in Dhaka Medical College Hospital, Dhaka, Bangladesh”. Journal of Bangladesh College of Physicians and Surgeons 38 (2020).
×

Citation

Citation: Md Harun Ar Rashid Talukder., et al. “COVID-19 Infection in Patient with Sudden Onset Anosmia in the Current Pandemic: Experience in Private Otolaryngology Practice". Acta Scientific Clinical Case Reports 1.11 (2020): 28-31.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.278

Indexed In