Meditrina Heart Centre, Civil Hospital, Panchkula, Haryana, India.
*Corresponding Author: Ankur Gupta, Meditrina Heart Centre, Civil Hospital, Panchkula, Haryana, India.
Received: September 01, 2020; Published: September 16, 2020
Familial Hypercholesterolemia (FH) is an inherited defect in the body where it cannot recycle LDL properly. FH is caused by mutations in the genes coding for the Low-Density Lipoprotein Receptor (LDLR), apolipoprotein B (ApoB) or Proprotein Convertase Subtilase/ Kexin type 9 (PCSK9). This defect leads to severe elevations in total cholesterol (CH) and low-density lipoprotein cholesterol (LDLc) in the body. FH has a huge impact on molecular biology, clinical medicine and public health.
Citation: Ankur Gupta. “Familial Hypercholesterolemia - A Hidden Danger". Acta Scientific Clinical Case Reports 1.9 (2020): 19-21.
Copyright: © 2020 Ankur Gupta. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.