Familial Hypercholesterolemia (FH) is an inherited defect in the body where it cannot recycle LDL properly. FH is caused by mutations in the genes coding for the Low-Density Lipoprotein Receptor (LDLR), apolipoprotein B (ApoB) or Proprotein Convertase Subtilase/ Kexin type 9 (PCSK9). This defect leads to severe elevations in total cholesterol (CH) and low-density lipoprotein cholesterol (LDLc) in the body. FH has a huge impact on molecular biology, clinical medicine and public health.

References

Citation

Citation: Ankur Gupta. “Familial Hypercholesterolemia - A Hidden Danger". Acta Scientific Clinical Case Reports 1.9 (2020): 19-21.

Copyright

Copyright: © 2020 Ankur Gupta. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.