Acta Scientific Clinical Case Reports

Case Report Volume 1 Issue 9

A Curious Case of Churg-Strauss

Kathleen McCabe and Imran Naqvi*

Department of Internal Medicine, The Jewish Hospital, Bon Secours Mercy Health, Cincinnati, OH, USA

*Corresponding Author: Imran Naqvi, Department of Internal Medicine, The Jewish Hospital, Bon Secours Mercy Health, Cincinnati, OH, USA.

Received: July 29, 2020; Published: August 24, 2020



Eosinophilic granulomatosis with polyangiitis (EGPA), formally known as Churg-Strauss, is a rare multisystem vasculitis characterized by asthma, rhinosinusitis and eosinophilia. The lungs are the most common organ system affected, followed by the skin. Extrapulmonary organ involvement, specifically cardiac involvement, is the leading cause of morbidity and mortality associated with the disease [1]. Disease remission is usually achieved with high dose corticosteroids or immunosuppressive therapy. The clinical features of EGPA typically evolve over several stages, which include a prevasculitic or prodromal stage, an eosinophilic stage, and finally, a life-threatening vasculitic stage. Historically, EGPA was a pathologic diagnosis, meaning that overt vasculitis had to be present in order to establish a diagnosis; however, nearly forty-percent of patients with EGPA present with asthma, pulmonary infiltrates and eosinophilia prior to the development of vasculitis [1-3]. The American College of Rheumatology (ACR) implemented a diagnostic criterion that encompasses a clinical approach, which allows for the diagnosis of EGPA to be made, even when there is no pathologic evidence of vasculitis. This allows for early recognition of disease and prompt initiation of treatment, which may lead to improved outcomes. We introduce a patient who was misdiagnosed with bacterial pneumonia on three separate occasions, but was later found to have EGPA despite lacking pathologic evidence of vasculitis.

Keywords: Churg-Strauss; Eosinophilic Granulomatosis with Polyangiitis; Eosinophilia; Vasculitis; Asthma



Citation: Kathleen McCabe and Imran Naqvi. “A Curious Case of Churg-Strauss”. Acta Scientific Clinical Case Reports 1.9 (2020): 19-21.


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