Abstract

Breast cancer is one the leading cancers in women of reproductive age. Recent advances in early diagnostic and treatment plans have improved the prognosis and leads to successful treatment of these patients. This report discussed the importance of discussing fertility preservation options with young women with diagnosed with breast cancer and the challenges faced in the decision making of the patient.

The importance of a team of experts to involve closely with the patient to help in decision making will definitely help in the overall well being of the patient, to avoid regrets, post cancer treatment and recovery.

Keywords: Breast Cancer; Fertility; Patient

References

1. Hady El Hachem., et al. “Fertility Preservation in Breast Cancer Patients”. Future Oncology 10.10 (2014): 1767-1777.
2. DeSantis C., et al. “Breast cancer statistics”. CA: A Cancer Journal for Clinicians 64.1 (2014): 52-62.
3. Kim Hoon., et al. “Fertility preservation for patients with breast cancer: The Korean Society for Fertility Preservation clinical guidelines”. Clinical and Experimental Reproductive Medicine 44.4 (2017): 181-186.
4. Partridge AH., et al. “Web-based survey of fertility issues in young women with breast cancer”. Journal for Clinical Oncology 22 (2004): 4174-4183. 
5. Lambertini M., et al. “Cancer and fertility preservation: international recommendations from an expert meeting”. BMC Medicine 14 (2016): 1. 
6. Loren AW., et al. “Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update”. Journal for Clinical Oncology 31 (2013): 2500-2510. 
7. Munoz M., et al. “SEOM clinical guideline of fertility preservation and reproduction in cancer patients (2016)”. Clinical and Translational Oncology 18 (2016): 1229-1236.
8. Kim J and Mersereau JE. “Early referral makes the decision-making about fertility preservation easier: a pilot survey study of young female cancer survivors”. Support Care Cancer 23 (2015): 1663-1667. 
9. Ethics Committee of American Society for Reproductive Medicine. “Fertility preservation and reproduction in patients facing gonadotoxic therapies: a committee opinion”. Fertility and Sterility 100 (2013): 1224-1231.
10. Borini A., et al. “Cumulative pregnancy rates resulting from the use of fresh and frozen oocytes: 7 years' experience”. Reproductive BioMedicine Online 12 (2006): 481-486.
11. Grifo JA and Noyes N. “Delivery rate using cryopreserved oocytes is comparable to conventional in vitro fertilization using fresh oocytes: potential fertility preservation for female cancer patients”. Fertility and Sterility 93 (2010): 391-396.
12. Kim TJ., et al. “Vitrification of oocytes produces high pregnancy rates when carried out in fertile women”. Fertility and Sterility 93 (2010): 467-474.
13. Checa Vizcaino MA., et al. “The effects of letrozole on ovarian stimulation for fertility preservation in cancer-affected women”. Reproductive BioMedicine Online 24 (2012): 606-610.
14. Domingo J., et al. “Ovarian response to controlled ovarian hyperstimulation in cancer patients is diminished even before oncological treatment”. Fertility and Sterility 97 (2012): 930-934.
15. Kim J., et al. “Long-term safety of letrozole and gonadotropin stimulation for fertility preservation in women with breast cancer”. The Journal of Clinical Endocrinology and Metabolism 101 (2016): 1364-1371.
16. Oktay K., et al. “Letrozole reduces estrogen and gonadotropin exposure in women with breast cancer undergoing ovarian stimulation before chemotherapy”. The Journal of Clinical Endocrinology and Metabolism 91 (2006): 3885-3890.
17. Revelli A., et al. “Is letrozole needed for controlled ovarian stimulation in patients with estrogen receptor-positive breast cancer?” Gynecological Endocrinology 29 (2013): 993-996.
18. Turan V., et al. “Safety and feasibility of performing two consecutive ovarian stimulation cycles with the use of letrozole-gonadotropin protocol for fertility preservation in breast cancer patients”. Fertility and Sterility 100 (2013): 1681-1685.e1.
19. Donnez J and Dolmans MM. “Ovarian cortex transplantation: 60 reported live births brings the success and worldwide expansion of the technique towards routine clinical practice”. Journal of Assisted Reproduction and Genetics 32 (2015): 1167-1170.
20. Bigorie V., et al. “Ovarian metastases from breast cancer: report of 29 cases”. Cancer 116 (2010): 799-804.
21. Pimentel C., et al. “Ovarian metastases from breast cancer: a series of 28 cases”. Anticancer Research 36 (2016): 4195-4200.
22. Benedict Catherine., et al. “Fertility preservation and cancer: challenges for adolescent and young adult patients.” Current Opinion in Supportive and Palliative Care 10.1 (2016): 87-94.
23. Zebrack B., et al. “‘Cancer sucks’ and other ponderings by adolescent and young adult cancer survivors”’. Journal of Psychosocial Oncology 32.1 (2014): 1-15.
24. Meirow D., et al. “Toxicity of chemotherapy and radiation on female reproduction”. Clinical Obstetrics and Gynecology 53.4 (2010): 727-739.
25. Meistrich ML. “Male gonadal toxicity”. Pediatric Blood Cancer 53.2 (2009): 261-266. 

Citation

Citation: Nanda Rajaneesh and Carunya Mannan. “A Difficult Decision in Fertility Preservation in a Young Patient with Breast Cancer: A Case Report”. Acta Scientific Clinical Case Reports 1.9 (2020): 13-16.

Copyright

Copyright: © 2020 Nanda Rajaneesh and Carunya Mannan. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.