Acta Scientific Clinical Case Reports

Case Report Volume 2 Issue 10

Scleroderma Renal Crisis with Normal Blood Pressure: A Diagnostic Dilemma Solved by Renal Biopsy

Anirban Sen, Atanu Pal* and Ankit Ray

Department of Nephrology, IPGMER and SSKM, Kolkata, India

*Corresponding Author: Atanu Pal, Department of Nephrology, IPGMER and SSKM, Kolkata, India.

Received: September 13, 2021; Published: September 24, 2021


  Systemic sclerosis is an autoimmune disorder involving skin, gastro-intestinal tract, lungs, kidneys and heart and can present with a variety of manifestations like esophageal dysmotility, pulmonary fibrosis, hypertension and renal dysfunction. Scleroderma renal crisis is a dreaded complication of systemic sclerosis presenting as rapidly progressive renal dysfunction and accelerated hypertension. However around 10% of the patients with this condition have normal blood pressure which makes it difficult to diagnose early and have poor outcome. Here we present a case of normotensive scleroderma renal crisis in a 48 year old female, who presented with clinical signs of systemic sclerosis and unexplained renal dysfunction. The diagnosis was made with the help of immunological profile and renal biopsy, but the renal function of the patient did not improve and she remains dialysis dependent.

Keywords: Systemic Sclerosis; Scleroderma Renal Crisis; Normotensive Scleroderma Renal Crisis; Rapidly Progressive Renal Failure; Onion Skinning of Arterioles; Autoantibodies


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Citation: Anirban Sen., et al. “Scleroderma Renal Crisis with Normal Blood Pressure: A Diagnostic Dilemma Solved by Renal Biopsy". Acta Scientific Clinical Case Reports 2.10 (2021): 52-57.


Copyright: © 2021 Anirban Sen., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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