Acta Scientific Clinical Case Reports

Conceptual Paper Volume 2 Issue 8

The Ropy Ossein-Chondromyxoid Fibroma

Anubha Bajaj*

Department of Histopathology, Panjab University/A.B. Diagnostics, India

*Corresponding Author: Anubha Bajaj, Department of Histopathology, Panjab University/A.B. Diagnostics, India.

Received: June 24, 2021; Published: July 17, 2021


Chondromyxoid fibroma is an exceptional, benign, gradually progressive cartilaginous neoplasm initially scripted by Jaffe and Lichtenstein in 1948 [1]. World Health Organization defines chondromyxoid fibroma as a “benign tumour characterized by lobules of spindle-shaped or stellate cells that proliferate within an abundant intercellular matrix that can be myxoid, chondroid or fibrous in nature”. Classically, the benign chondromyxoid fibroma displays incomplete cartilaginous differentiation.


  1. Jaffe HL and Lichtenstein L “Chondromyxoid fibroma of bone: a distinctive benign tumor likely to be mistaken especially for chondrosarcoma”. Archives of Pathology 45 (1948): 541-551.
  2. Elsamanody A., et al. “Chondromyxoid Fibroma of the Mastoid: A Rare Entity with Comprehensive Literature Review”. The Journal of International Advanced Otology1 (2020): 117-122.
  3. Romeo S., et al. “Heterogeneous and complex rearrangements of chromosome arm 6q in chondromyxoid fibroma: delineation of breakpoints and analysis of candidate target genes”. The American Journal of Pathology 177 (2010): 1365-1376.
  4. Scheila MG., et al. “Chondromyxoid fibroma of the nasal bone”. International Archives of Otorhinolaryngology 13 (2009): 117-120.
  5. Oh N., et al. “Chondromyxoid fibroma of the mastoid portion of the temporal bone: MRI and PET/CT findings and their correlation with histology”. Ear, Nose and Throat Journal: SAGE Journals 92 (2013): 201-203.
  6. Wang J., et al. “Chondromyxoid fibroma of the petrous apex”. The Journal of Neuroradiology 38 (2011): 255-256.
  7. Hakan T and Vardar Aker F “Chondromyxoid fibroma of frontal bone: A case report and review of the literature”. Turkish Neurosurgery 18 (2008): 249-253.
  8. Thompson AL., et al. “Chondromyxoid fibroma of the mastoid facial nerve canal mimicking a facial nerve schwannoma”. Laryngoscope 119 (2009): 1380-1383.
  9. Image 1 and 2 Courtesy:
  10. Image 3 Courtesy: Pathology outlines.
  11. Image 4 Courtesy: Libre Pathology.
  12. Image 5 Courtesy: Journal of Scientific society.
  13. Image 6 Courtesy: SM Journals.
  14. Image 7 Courtesy: Atlas of genetics and cytogenetics in oncology.
  15. Image 8 Courtesy: BMJ Case Reports.


Citation: Anubha Bajaj. “The Ropy Ossein-Chondromyxoid Fibroma". Acta Scientific Clinical Case Reports 2.8 (2021): 41-47.


Copyright: © 2021 Anubha Bajaj. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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