Acta Scientific Women's Health (ASWH)(ISSN: 2582-3205)

Research Article Volume 2 Issue 12

Effect of Interpregnancy Interval on Adverse Maternal and Perinatal Outcomes at Katutura Regional Referral Hospital in Namibia: A Retrospective Cohort Study, 2005 to 2015

Lyasimana Lithaneninn Ndaninginan1,3, Pendo Mlay1, Raziya Gaffur1, Benjamin Joseph Nggada3 and Michael Johnson Mahande2*

1Department of Obstetrics and Gynecology, Kilimanjaro Christian Medical Center, Moshi, Tanzania
2Department of Epidemiology and Biostatistics, Institute of Public Health, Kilimanjaro Christian Medical University College, Moshi, Tanzania
3Department of Obstetrics and Gynecology,Katutura Referral Regional Hospital, Windhoek, Namibia

*Corresponding Author: Michael Johnson Mahande, Department of Epidemiology and Biostatistics, Institute of Public Health, Kilimanjaro Christian Medical University College, Moshi, Tanzania.

Received: September 05, 2020; Published: November 18, 2020

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Abstract

Objective: To determine the effect of interpregnancy interval (IPI) on adverse and perinatal outcomes among Namibian women who delivered at Katutura regional referral Hospital from January 2005 to December 2015.

Methods: Retrospective cohort study conducted at Katutura regional referral hospital Windhoek in Namibia. A total of 3219 women who had two consecutive singleton deliveries from 2005 - 2015 were studied. The outcome of interest were maternal outcomes (preeclampsia, anemia and maternal death) and perinatal outcomes (preterm birth, low birth weight, neonatal intensive care unit and perinatal death).

Data were analyzed using STATA version 15. A log-binomial regression model was used to estimate the relative risk for adverse outcomes with their respective 95% confidence intervals (CIs). A robust variance estimator was used to take into account for repeated observations/births from the same mother.

Results: Nearly half (52.9%) of the women had optimal interpregnancy interval (24 - 59 months). Women who conceived within a short IPI had increased risk of preeclampsia in their next pregnancy (ARR 2.70.95% CI 1.55 - 4.71). Both short and long IPI were associated with an increased risk of anemia (ARR 2.76; 95% 1.59 - 3.94) and (ARR 2.51; 95% 1.38 - 4.57) respectively. Short IPI was associated with 3% maternal death. Short IPI was associated with increased risk of preterm birth (ARR1.67; 95% 1.36 - 2.06) and low birth weight (ARR1.34; 95% 1.03 - 1.74), respectively.

Conclusion: We confirm that both short and long IPI were associated with adverse maternal and perinatal outcomes. Our finding suggest a need for a targeted intervention such as modern contraceptive use to promote optimal IPI.

Keywords: Interpregnancy Interval; Adverse Maternal Outcomes; Adverse Perinatal Outcomes; Namibia

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References

  1. Fareid S., et al. “Effect of Interpregnancy Interval on Pregnancy Outcome among Pregnant Women Attending Delivery at Belqas hospital”. IOSR Journal of Nursing and Health Science4 (2015): 5-13.
  2. Conde-Agudelo A., et al. “Effect of the interpregnancy interval on perinatal outcomes in Latin America”. Obstetrics and Gynecology 2 (2005): 359‐366.
  3. Mahande MJ and Obure J. “Effect of interpregnancy interval on adverse pregnancy outcomes in northern Tanzania: a registry-based retrospective cohort study”. BMC Pregnancy and Childbirth1 (2016): 1-9.
  4. World Health Organisation. Report of a WHO Technical Consultation on Birth Spacing (2007).
  5. Kozuki N and Walker N. “Exploring the association between short/long preceding birth Intervals and child mortality: Using reference birth interval children of the same mother as comparison”. BMC Public Health3 (2013): S6.
  6. Gemmill A and Lindberg LD. “Short interpregnancy intervals in the United States”. Obstetrics and Gynecology 1 (2013): 64-71.
  7. Hanley GE., et al. “Interpregnancy interval and adverse pregnancy outcomes an analysis of successive pregnancies”. Obstetrics and Gynecology 3 (2017): 408-415.
  8. Conde-Agudelo A. “Maternal morbidity and mortality associated with interpregnancy interval: cross sectional study”. British Medical Journal 7271 (2000): 1255-1259.
  9. Conde-Agudelo A., et al. “Effect of Birth Spacing on Maternal, Perinatal, infant and Child Health: A systemic Review of Causal Mechanisms”. American Journal of Obstetrics and Gynecology2 (2012): 342-349.
  10. Miller JE. “Birth intervals and perinatal health: an investigation of three hypotheses”. Family Planning Perspectives 2 (1991): 62‐70.
  11. Towriss CA and Timæus IM. “Contraceptive use and lengthening birth intervals in rural and urban Eastern Africa”. Demographic Research64 (2018): 2027-2052.
  12. Yeakey MP., et al. “How Contraceptive Use Affects Birth Intervals: Results of a Literature Review”. Studies in Family Planning3 (2009): 205-214.
  13. Bibi S., et al. “Postpartum contraception utilization and its impact on inter pregnancy interval among mothers accessing maternity services in the public sector hospital of Hyderabad Sindh”. Pakistan Journal of Medical Sciences 6 (2019): 1482-1487.
  14. Smith DP. “Breastfeeding, contraception, and birth intervals in developing countries”. Studies in Family Planning 3 (1985): 154-163.
  15. Exavery A., et al. “Levels and correlates of nonadherence to WHO recommended inter-birth intervals in Rufiji, Tanzania”. BMC Pregnancy Childbirth 12 (2012): 1-8.
  16. Sanga LA., et al. “Inter-pregnancy interval and associated adverse maternal outcomes among women who delivered at Kilimanjaro Christian Medical Centre in Tanzania, 2000-2015”. PLoS ONE2 (2020): e0228330.
  17. WHO recommendations on antenatal care for a positive pregnancy experience.2017; World Health Organization Newborns: reducing mortality (2017).
  18. Nsangamay T and Mash R. “How to improve the quality of care for women with postpartum hemorrhage at Onandjokwe Hospital, Namibia: quality improvement study”. BMC Pregnancy and Childbirth (2019): 19-489.
  19. Heemelaar S., et al. “Measuring maternal near-miss in a middle-income country: assessing the use of WHO and sub-Saharan Africa maternal near-miss criteria in Namibia”. Global Health Action 1 (2019): 1646036.
  20. Lilungulu A., et al. “Spectrum of maternal and perinatal outcomes among parturient women with preceding short inter pregnancy interval at Bugando Medical Centre, Tanzania”. Maternal Health, Neonatology and Perinatology 1 (2015): 1.
  21. Cecatti JG., et al. “The associations between inter‐pregnancy interval and maternal and neonatal outcomes in Brazil”. Maternal and Child Health Journal 12 (2008): 275-281.
  22. Cunningham F., et al. “Hypertensive Disorders”. In: Cunningham F, Leveno KJ, Bloom SL, et al. eds. Williams Obstetrics. 25th New York, NY: McGraw-Hill (2018): 1564-1166.
  23. Rasmussen K. “Is there a causal relationship between iron deficiency or iron-deficiency anemia and weight at birth, length of gestation and perinatal mortality?” Journal of Nutrition 131 (2001): 590S-601S.
  24. Milman N. “Oral iron prophylaxis in pregnancy: not too little and not too much”. Journal of Pregnancy (2012): 514345.
  25. Haider BA., et al. “Anemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis”. British Medical Journal 346 (2013): f 3443.
  26. Making health service adolescent friendly: Developing national quality standard for adolescent friendly health services. Geneva: WHO (2012).
  27. Kalafa E and Thilaganatha B. “Cardiovascular origin of preeclampsia”. Current Opinion Obstetrics and Gynecology 6 (2017): 383-389.
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Citation

Citation: Michael Johnson Mahande., et al. “Effect of Interpregnancy Interval on Adverse Maternal and Perinatal Outcomes at Katutura Regional Referral Hospital in Namibia: A Retrospective Cohort Study, 2005 to 2015". Acta Scientific Women's Health 2.12 (2020): 02-09.




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Impact Factor0.539

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