Acta Scientific Pharmaceutical Sciences (ASPS) (ISSN: 2581-5423)

Review Article Volume 4 Issue 12

Phytochemical Composition and Pharmacological Potential of Adhatoda zeylanica Medic. Syn. A. vasica L. Nees

Harsukh Chharang1, Lakha Ram2, Ashok K Kakodia3 and Raaz K Maheshwari1*

1Department of Chemistry, SBRM Govt PG College, Nagaur, Rajasthan, India
2Department of Chemistry, JNMP Govt PG College, Phalodi, Jodhpur, Rajasthan, India
3Department of Chemistry, SGG G PG College, Banwara, Rajasthan

*Corresponding Author: Raaz K Maheshwari, Department of Chemistry, SBRM Govt PG College, Nagaur, Rajasthan, India.

Received: September 15, 2020; Published: November 07, 2020

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Abstract

  Innumerable natural products with inherent potential biological activity procured from plants have played a significant role in improving the human health since the dawn of civilisation. As more than 50% of modern clinical drugs originate from natural products. Therefore, based on latter, the approach to new drug discovery and its development in the pharmaceutical industry has emerged significantly. A. vasica is a good source of pyrroloquinoline alkaloids such as vasicine, vasicol, adhatodine, vasicinone, vasicinol, vasicinolone etc. which are the chief constituents of different extracts of the plant. These compounds have shown many biological and pharmacological activities viz. anti-malarial, anti-inflammatory, antioxidant, antidiabetic, anti-bacterial, anti-cancer etc. Further, Adhatoda leaves have been used extensively in Ayurvedic medicine for the treatment of diarrhea, dysentery, tuberculosis, skin diseases, vomiting and leprosy etc. Herbal medicine is still the mainstay of about 75-80% of the world population, mainly in the developing countries, for primary health care because of better cultural acceptability, better compatibility with the human body and lesser side effects. However, the last few years have seen a major increase in their use in the developed world. As far as contemporary drugs are concerned they must be further characterized after their pharmacological screening by studying the pharmacokinetic and pharmacodynamic properties, including toxicity. Therefore, the present communication enumerate the phytochemical composition and pharmacological potential of A. vasica.

Keywords: Adhatoda vasica; Secondary Metabolites; Pyrroloquinoline Alkaloids; Biological Activities

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Citation

Citation: Raaz K Maheshwari., et al. “Phytochemical Composition and Pharmacological Potential of Adhatoda zeylanica Medic. Syn. A. vasica L. Nees".Acta Scientific Pharmaceutical Sciences 4.12 (2020): 16-21.



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