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Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Case Report Volume 4 Issue 8

Hepatic Rupture Complicating HELLP Syndrome and Pre-existent Antiphospholipid Syndrome with Cerebral Venous Sinus Thrombosis

Chinmayi Patkar-Kattimani1*, Riddhi Rathod1, Dinesh Sagtani2 and Prasad Kattimani1

1Specialty Doctor, Department of Anaesthesia and Intensive Care, Queen’s Hospital, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, Essex, United Kingdom
2Consultant, Department of Anaesthesia and Intensive Care, Queen’s Hospital, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, Essex, United Kingdom

*Corresponding Author: Chinmayi Patkar-Kattimani, Specialty Doctor, Department of Anaesthesia and Intensive Care, Queen’s Hospital, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, Essex, United Kingdom.

Received: June 08, 2020; Published: July 28, 2020

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Abstract

 Antiphospholipid syndrome is associated with HELLP (Haemolysis, Elevated Liver enzymes and Low Platelets) syndrome as a continuum of thrombotic microangiopathies. Subcapsular liver haematoma is a rare presentation of HELLP syndrome. A 38-year-old woman at 33 weeks gestation presented with HELLP syndrome complicated by acute hepatic rupture. She had background history of antiphospholipid syndrome with cerebral venous sinus thrombosis. Postoperative course was complicated by hepatic failure, sepsis and haemodynamic instability which was managed successfully. Anaesthetists need to be aware of serious complications like haemorrhage, thrombosis and multi-organ failure when presented with HELLP syndrome and antiphosholipid syndrome.

Keywords: HELLP Syndrome; Antiphospholipid Syndrome; Cerebral Venous Sinus Thrombosis; Subcapsular Liver Haematoma; Hepatic Rupture

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References

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Citation

Citation: Chinmayi Patkar-Kattimani., et al. “Hepatic Rupture Complicating HELLP Syndrome and Pre-existent Antiphospholipid Syndrome with Cerebral Venous Sinus Thrombosis". Acta Scientific Pharmaceutical Sciences 4.8 (2020): 112-115.




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