Coronaviruses and influenza viruses, the pandemic viruses can cause acute respiratory distress syndrome (ARDS) contributing to lethally acute lung injuries (ALI) and death. Activation of nuclear factor erythroid 2 (nfe2)-related factor 2 (nrf2), a major regulator of antioxidant response element (ARE)-driven cytoprotective protein expression plays an critical role in preventing cells and tissues from oxidative-stress-induced injury. Both viral and bacterial infections can contribute to cytokine storm that results in increased oxidative stress. Vitamin C is beneficial to critical care management due to its important component of the cellular antioxidant system.

References

Citation

Citation: Attapon Cheepsattayakorn., et al. “Intravenous High-Dose and Supplementation of Vitamin C Can Effectively Prevent and Treat COVID-19?".Acta Scientific Pharmaceutical Sciences 4.7 (2020): 01-02.

Copyright

Copyright: © 2020 Attapon Cheepsattayakorn., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.