Muhammad Muhsin Fathuddin1,2* and Rafeedah Fathuddin1
1Department of Microbiology, Ahmadu Bello University, Zaria, Kaduna State, Nigeria
2Department of Microbiology, Kaduna State University, Kaduna, Kaduna State, Nigeria
*Corresponding Author: Muhammad Muhsin Fathuddin, Department of Microbiology, Kaduna State University, Kaduna, Kaduna State, Nigeria.
Received: November 23, 2020; Published: January 30, 2020
Background: Extracts of Curcuma longa rhizome extracts were investigated for their biological activity.
Methodology: The presence of phytochemicals and antitrypanosomal activities were investigated.
Results: The extracts contained the phytochemicals (Alkaloid, Anthraquinone, Carbohydrates, Cardiac Glycosides, Flavonoid, Glycosides, Phenols, Saponin, Steroid, Tannin and Triterpenes) in table 1 and 2. The extracts showed very good activity against the parasite from figure 1, 2 and 3.
Discussion: The presence of the phytochemical confirms their medicinal potentials. The crude extracts of Curcuma longa were analyzed in vitro for trypanocide activity on Trypanosoma brucei brucei at concentration 100.0 mg/ml, 50.0 mg/ml, 25 mg/ml, 12.5 mg/ml and 6.25 mg/ml. The best activity was seen in Petroleum ether extract, followed by the ethanol extract, then Chloroform which was still impressive.
Conclusion: The results obtained from this study show that the turmeric contains potential antimicrobial components which will be of great use for the advancement of remedies by pharmaceutical industries as a therapy against various diseases.
Keywords: Curcuma longa; Petroleum Ether; Chloroform; Ethanol; Antitrypanosomal Activity; Trypanosoma brucei brucei
Citation: Muhammad Muhsin Fathuddin and Rafeedah Fathuddin. “The Screening for the Antitrypanosomal Potentials of the Extracts of Curcuma longa L.". Acta Scientific Microbiology 4.2 (2021): 76-81.
Copyright: © 2021 Muhammad Muhsin Fathuddin and Rafeedah Fathuddin. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.