Republican Specialized Scientific and Practical Medical Center of Obstetrics and Gynecology Under the Ministry of Health of the Republic of Uzbekistan, Uzbekistan
*Corresponding Author: Mavlyanova NN, Republican Specialized Scientific and Practical Medical Center of Obstetrics and Gynecology Under the Ministry of Health of the Republic of Uzbekistan, Uzbekistan.
Received: June 16, 2020; Published: September 30, 2020
The article presents the results of molecular genetic studies of genes of biotransformation enzymes of xenobiotics of the first and second phase in pregnant women with fetal growth restriction syndrome. Using the del/del genotype variants of the GSTM1 and GSTT1 genes and G alleles of the GSTP1 gene, one can determine the prognosis of the risk of developing fetal loss syndrome, characterized by impaired detoxification during pregnancy.
Keywords: GSTM1; GSTT1; Fetal Growth Restriction Syndrome (FGRS)
Citation: Mavlyanova NN. “The Role of Xenobiotic Enzyme Genes of the First and Second Phases in the Pathogenesis of Fetal Growth Restriction Syndrome". Acta Scientific Microbiology 3.10 (2020): 84-89.
Copyright: © 2020 Mavlyanova NN. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.