Abstract

Background: Helicobacter pylori (H. pylori), a highly prevalent gastrointestinal organism, infects more than 50% of the global population. It is the most common risk factor for peptic ulcer disease, cancer stomach and gastric lymphoma.

Eradication therapy regimens for H. pylori are highly effective. However, bacterial resistance to antibiotics and patients non-adherence to the treatment regimens significantly increased the recurrence rates of H. pylori infection in the last few decades.

Study Aim: To assess the prevalence and possible risk factors of H. pylori recurrence in Egyptian patients after eradication therapy.

Patients and Methods: We evaluated and followed up 157 patients for one year after confirmed successful eradication of H. pylori infection. We investigated the patients at 3, 6, 9 and 12 months for recurrence of H. pylori infection using urea breath and stool antigen tests.

Results and Conclusion: We found a one-year recurrence rate of 19% after successful eradication therapy of H. pylori. The education level of the patients and alcohol consumption were the most significant predictors of H. pylori recurrence. The one-year recurrence rate in our study is high but comparable to those reported in the developing countries most probably due to high rates of re-infection and non-adherence to the preventive measures.

Keywords: H. pylori; Proton Pump Inhibitors; Eradication Therapy; Bacteria Resistance; Recurrence

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Citation

Citation: Mohamed AA Bassiony. “Recurrence of Helicobacter pylori Infection after Successful Eradication Therapy in Egyptian Patients”.Acta Scientific Gastrointestinal Disorders 3.9 (2020): 09-13.

Copyright

Copyright: © 2020 Mohamed AA Bassiony. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.