Acta Scientific Dental Sciences (ISSN: 2581-4893)

Review Article Volume 4 Issue 12

A Recommendation of PHTALOX® Mouthwash for Preventing Infection and Progression of COVID-19

Paulo Sérgio da Silva Santos1*, Bernardo da Fonseca Orcina2, Lucas Marques da Costa Alves3, Rodrigo Cardoso de Oliveira4, Mariana Schutzer Ragghianti Zangrando5 and Fabiano Vieira Vilhena6

1Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry of University of São Paulo, Brazil
2Postgraduate Student, Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry of University of São Paulo, Brazil
3Physician of Hospital Infection Control Committee, Hospital Estadual de Bauru, Brazil
4Department of Biological Sciences, Bauru School of Dentistry of University of São Paulo, Brazil
5Department of Prosthesis and Periodontology, Bauru School of Dentistry of University of São Paulo, Brazil
6Oral Health and Techonologies, Brazil

*Corresponding Author: Paulo Sérgio da Silva Santos, Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry of University of São Paulo, Brazil.

Received: November 13, 2020; Published: November 27, 2020

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Abstract

  The mouth has a significant role when it comes to the transmission process of SARS - CoV-2. This happens due to the spread of small droplets which makes the oral and oropharynx mucosa easy targets for the virus [1]. Therefore, the oral cavity is directly associated with the evolutionary process of SARS-CoV-2 in the inhalation of environmental particles in the air and in the sputum, because it can also be transmitted through saliva [2].

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References

  1. Carrouel F., et al. “Nanoparticles as Anti-Microbial, Anti-Inflammatory, and Remineralizing Agents in Oral Care Cosmetics: A Review of the Current Situation”. Nanomaterials, Basel1 (2020): 1-32.
  2. To KK., et al. “Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study”. Lancet Infection Diseases New York 20.5 (2020): 565-574.
  3. Xu H., et al. “High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa”. International Journal of Oral Science1 (2020): 8.
  4. Burton MJ., et al. “Use of antimicrobial mouthwashes (gargling) and nasal sprays by healthcare workers to protect them when treating patients with suspected or confirmed COVID-19 infection”. Cochrane Database System Review 5 (2020): CD013626.
  5. Nagatake T., et al. “Prevention of Respiratory Infections by Povidone-Iodine Gargle”. Dermatology, Basel. 204 (2002): 32-36.
  6. Meister TL., et al. “Virucidal Efficacy of Different Oral Rinses Against Severe Acute Respiratory Syndrome Coronavirus 2”. Journal of Infectious Diseases8 (2020): 1289-1292.
  7. Gottsauner MJ., et al. “A prospective clinical pilot study on the effects of a hydrogen peroxide mouthrinse on the intraoral viral load of SARS-CoV-2”. Clinical Oral Investigation 24 (2020): 3707-3713.
  8. Korneev D., et al. “Ultrastructural Aspects of Photodynamic Inactivation of Highly Pathogenic Avian H5N8 Influenza Virus”. Viruses, Basel.10 (2019): 955.
  9. Teodoro G., et al. “PHTALOX® Antimicrobial Action and Cytotoxicity: in vitro Study”. Journal of Dental Research 99 (SpecIss A): abstract number, 0839, 2020 IADR/AADR/CADR General Session (Washington, D.C., USA) (2020).
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Citation

Citation: Paulo Sérgio da Silva Santos., et al. “A Recommendation of PHTALOX® Mouthwash for Preventing Infection and Progression of COVID-19". Acta Scientific Dental Sciences 4.12 (2020): 111-112.



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