Acta Scientific Dental Sciences (ISSN: 2581-4893)

Review Article Volume 4 Issue 10

Linear IgA Disease - A Rare Sub Epithelial Disorder: A Current Appraisal

Shamimul Hasan*

Professor, Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India

*Corresponding Author: Shamimul Hasan, Professor, Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India.

Received: September 03, 2020; Published: September 26, 2020

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Abstract

  Linear IgA disease is a non hereditary, autoimmune sub epidermal bullous disease, characterized by the presence of linear deposition of IgA auto antibodies along the basement membrane zone. The disease has a bimodal occurrence, manifesting in both children and adults. The cause is usually obscure in childhood, although, adult onset cases are primarily due to drugs (vancomycin), malignancies and infections. Skin and several mucous membrane involvement usually occur, and oral lesions are rarely seen in the disease. Dapsone forms the mainstay of treatment along with corticosteroids.

Keywords: Dapsone; Desquamative Gingivitis; Immunofluorescence; Linear IgA Disease; Subepithelial Blistering

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References

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Citation

Citation: Shamimul Hasan. “Linear IgA Disease - A Rare Sub Epithelial Disorder: A Current Appraisal". Acta Scientific Dental Sciences 4.10 (2020): 100-104.



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