Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Research Article Volume 4 Issue 1

Phytochemical and Antimicrobial Activity of Solanum torvum Against Respiratory Tract Pathogens

M Rajathi D Modilal1*, R Sindhu2, R Cecily Rosemary Latha1 and R Anandan3

1PG and Research Department of Zoology, Holy Cross College, Tiruchirappalli, India
2Department of Biotechnology, Karpaga Vinayaga College of Engineering and Technology, Kanchipuram, India
3Department of Computer Science and Engineering, School of Engineering, VELS Institute of Science, Technology and Advanced Studies, Chennai, India

*Corresponding Author: M Rajathi D Modilal, PG and Research Department of Zoology, Holy Cross College, Tiruchirappalli, India.

Received: December 12, 2019; Published: December 26, 2019

×

Abstract

  Medicinal plants are extensively used to cure various infectious diseases in human beings, hence S. torvum was investigated for its activity against the isolated pathogens. The study was designed to screen and characterize the bacteria isolated from the respiratory tract infected patients. Phytochemical analysis of the plant showed the presence of alkaloids, terpenoids, flavonoids, saponins, steroids and phenols. Aqueous, ethanol and diethyl ether extract of S. torvum was prepared; four different concentrations of each extract was taken to determine the antibacterial activity against the isolated bacteria. The ethanolic extract of S. torvum showed highest antimicrobial activity in comparison to aqueous and diethyl ether extracts. Thus S. torvum has antimicrobial activity and can be used clinically to find novel antibacterial compounds for respiratory tract pathogens.

Keywords: Respiratory Tract Infections; Antibacterial Activity; Phytochemical Activity; S. torvum

×

References

  1. Sethi S., et al. “Antimicrobial activity of medicinal plants on respiratory tract pathogens”. IJBPR 4.2 (2013): 148-152.
  2. Roncevic N., et al. “Treatment of acute infections of the lower respiratory tract in children”. Medicinski Pregled 55 (2002): 299-304. 
  3. Sazawal S and Black RE. “Effect of pneumonia case management on mortality in neonates, infants, and preschool children: a meta-analysis of community-based trials”. Lancet Infection Disease 3 (2003): 547-556. 
  4. Ponni V., et al. “Screening of bioactive potentials and phytochemical nature of Solanum trilobatum extracts”. Journal of basic and applied biology 3.3-4 (2000): 134-136.
  5. Qadri SMH. “Incidence of bacterial respiratory pathogens and their susceptibility to common antibacterial agents”. Journal of the National Medical Association 85 (1993): 388.
  6. WHO Library cataloguing-in-publication data: Global status report on non- communicable diseases 68 (2010). 
  7. Samy RP., et al. “Preliminary screening of ethnomedicinal plants from India”. European Review for Medical and Pharmacological Sciences 12 (2008): 1-7.
  8. Karou D., et al. “Antibacterial activity of alkaloids from Sida acuta”. African Journal of Biotechnology 5.2 (2005): 195-200.
  9. Jaiswal BS. “Solanum Torvum: A Review of Its Traditional Uses, Phytochemistry And Pharmacology”International Journal of Pharma and Bio Sciences 3.4 (2012): 104 – 111.
  10. Kolawale AS., et al. “Prevalence of urinary tract infections among patients attending Dalhatu Araf Specialist Hospital, Lafia, Nasarawa State, Nigeria”. International Journal of Medical Sciences 1.5 (2009): 163-167.
  11. Cheesborough M. District Laboratory Practice in Tropical Countries, Microbiology second edition Cambridge University Press 2 (2006): 158-195. 
  12. Cowan SJ and Steel KJ. Cowan and Steel manual for identification of medical bacteria, 2nd edn Cambridge University Press, London (1974): 176-232. 
  13. Harborne JB. “Methods of extraction and isolation”. In: Phytochemical Methods”. Chapman and Hall, London (1998): 60-66.
  14. Perez C., et al. “Antibiotic assay by agar-well diffusion method”. Acta Biologiae Ethnomedicine Experimentalist 15 (1990): 113-115.
  15. Kayalvizhi J., et al. “Studies on the Physico-Phytochemical Properties and Hepatoprotective Effect Of Solanum Torvum Swartz In CCl4 Induced Experimental Toxicity In Albino Rats”. International Journal of Pharmacy and Pharmaceutical Sciences 4.15 (2012): 0975-1491.
  16. Cushnie TPT and Lamb AJ. “Antimicrobial activity of flavonoids”. International Journal of Antimicrobial Agents 26.5 (2005): 343-356.
  17. De Sousa RR., et al. “Phosphoprotein levels, MAPK activities and NFkappaB expression are affected by fisetin”. Journal of Enzyme Inhibition and Medicinal Chemistry 22.4 (2007): 439-444.
  18. Rievere C., et al. “Polyphenols isolated from antiradical extracts of Mallotus metcalfianus”. Phytochemistry 70 (2009): 86-94.
  19. Aguinaldo AM., et al. “Phytochemistry”. In: Guevara BQ. (ed.) A guide book to plant screening phytochemical and biological. Manila: University of Santo Tomas (2005).
  20. Mohanta TK., et al. “Evaluation of antimicrobial activity and phytochemical screening of oils and nuts of Semicarpus anacardium”. Scientific Research and Essays 2.11 (2011): 486-490.
  21. De-Lucca A., et al. “Fungal properties of CAY-1, a plant saponin, for emerging fungal pathogens, 45th inter science conference in antimicrobial agents and chemotherapy abstract (2005): 180.
  22. Mandal P., et al. “Antimicrobial activity of Saponins from Acacia auriculiformis”. Fitoterapia 76.5 (2005): 462-565.
  23. Manjunatha BK. “Antibacterial activity of Pterocarpus santalinus”. Indian Journal of Pharmaceutical Sciences 68.1 (2006): 115-116.
  24. Arts IC and Hollman PC. “Polyhenols are disease risk in epidemiological studies”. The American Journal of Clinical Nutrition 81 (2005): 317-325.
  25. Scalbert A., et al. “Dietary polyphenols and the prevention of diseases”. Critical Reviews in Food Science and Nutrition 45 (2005): 287-306.
  26. Abubakar EMM. “Antibacterial efficacy of stem bark extracts of Mangifera indica against some bacteria associated with respiratory tract infections”. Scientific Research and Essay 4.10 (2009): 1031-1037.
×

Citation

Citation: M Rajathi D Modilal., et al. “Phytochemical and Antimicrobial Activity of Solanum torvum Against Respiratory Tract Pathogens". Acta Scientific Pharmaceutical Sciences 4.1 (2020): 62-66.



Member In



News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for March Issue
    The last date for submission of articles for regular Issues is March 15, 2020.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US