Acta Scientific Ophthalmology

Research ArticleVolume 1 Issue 1

Mean Platelet Volume in Retinal Vein Occlusion

Lagan Paul1, Shalini Singh1*, Manisha Agarwal1, Lokesh Chauhan2, Rahul Mayor1 and Ankita Shrivastav1

1Vitreoretina Services, Dr. Shroff’s Charity Eye Hospital, New Delhi, India
2Statistics and Research, Dr. Shroff’s Charity Eye Hospital, New Delhi, India

*Corresponding Author: Shalini Singh, Vitreoretina Services, Dr. Shroff’s Charity Eye Hospital, New Delhi, India.

Received: July 10, 2018; Published: July 28, 2018

Citation: Shalini Singh., et al.“Mean Platelet Volume in Retinal Vein Occlusion”. 1.1 (2018).


Objective: To evaluate the levels of mean platelet volume (MPV) in patients with retinal vein occlusion (RVO) secondary to thromboembolic occlusion.

Design: Prospective case control study.

Participants: A total of 104 patients were enrolled in the study including 52 consecutive patients with recent episode (less than one month) of retinal vein occlusion (central, hemi-central and branch retinal vein occlusion) who visited a tertiary eye institute in India from August 2014 to June 2015 and 52 patients were age and gender matched controls. Both hypertensives and non-hypertensives were included.

Methods: Ophthalmic evaluation at initial visit included snellen’s best corrected visual acuity (BCVA), intraocular pressure assessment and detailed ocular examination. Optical Coherence Tomography (OCT) was done at the first visit for each patient and fundus fluorescein angiography (FFA) was done at 3 months if required. Complete hemogram and MPV was estimated at the first visit for every patient. A morning sample of blood was collected of all 104 patients and sent for complete hemogram and MPV evaluation to a single laboratory.

Results: The mean platelet volume was higher (10.402 ± 1.9 femtolitre (fl) in the patients having RVO versus the control group (10.242 ± 1.9 fl) but the difference was not found to be statistically significant (t-test, p value 0.838).

Keywords: Mean Platelet Volume; Retinal Vein Occlusion

Copyright: © 2018 Shalini Singh., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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