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Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Research Article Volume 6 Issue 6

Boosting Immunity to Compat Covid-19 Virus: A Prospective of Bioplot Validation Study Using Acacia Gums and Adansonia digitata Pulp

Ahmed AM Elnour1,2,3*, Mohamed ES Mirghani1, Djabir Daddiouaissa1, Nassereldeen A Kabbashi1, Omayma Sabir4, Khalid Hamid Musa5, El Bashier Sallam6, Elmoubasher Abu Baker Abd Farag7, Abdelgadir Elfadil Abdelgadir8, Zahra Haroun9 and Ibrahim Bani10,11

1Bioenvironmental Engineering Research Center (BERC), Biotechnology Engineering Department, Kuliyyah (Faculty) of Engineering, International Islamic University, Malaysia (IIUM), Kuala Lumpur, Malaysia
2International Institute for Halal Research and Training, Level 3, KICT Building, IIUM, Kuala Lumpur, Malaysia
3Institute of Gum Arabic and Desertification Studies (IGADS), University of Kordofan, Sudan
4Al Nileen Medical School, Al Nileen University, Khartoum, Sudan
5Department of Food Science and Human Nutrition, College of Agriculture and Veterinary Medicine; Qassim University, Kingdom of Saudi Arabia
6Freelance Global and Public Health Expert (FGPHE), Sudan
7Department of Public Health, Communicable Diseases Control, Ministry of Health, Doha, Qatar
8Department of Environmental Science, Faculty of Science and Technology, Al-Neelain University, Sudan
9Longwarry Medical Center (LMD), Longwarry, Australia
10College of Medicine, Ajman University, Ajman, UAE
11Centre of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, UAE

*Corresponding Author: Ahmed AM Elnour, Bioenvironmental Engineering Research Center (BERC), Biotechnology Engineering Department, Kuliyyah (Faculty) of Engineering, International Islamic University, Malaysia (IIUM), Kuala Lumpur, Malaysia and International Institute for Halal Research and Training, Level 3, KICT Building, IIUM, Kuala Lumpur, Malaysia and Institute of Gum Arabic and Desertification Studies (IGADS), University of Kordofan, Sudan.

Received: April 25, 2022; Published:

Abstract

Background: The innate immune system (IIS) prevents the host from being infected by pathogenic organisms, including viruses, bacteria, parasites, and fungi. This keen action is supplemented by an increased metabolism level, which needs energy sources and substrates for strengthening and controlling molecules, eventually obtained from the superfood.

Aims: This is the first study that investigates the micronutrient values (MNVs) and microbial contents of an optimum blend formula at a ratio of 5:3:2 (grams) prepared for Acacia gums (Acacia seyal, Acacia sengal and Adansonia digitata L pulp (ADLPs)), respectively.

Objective: The study's main objective is to develop an optimal formula using a specific combination of AGs and ADLPs to support the infected COVID-19 patient's IIS based on MNVs.

Methods: We investigated the MNVs, including microbial content and vitamins, using High-Performance Liquid Chromatography (HPLC) and short-chain fatty acids (SCFA) from AGs, using an artificial stomach. We conducted a randomized trial and a pilot study to identify the effects of the daily optimum blended formula (OPF) (3 in 1) on Covid-19 patients. They gave one hundred five participants the blended (5:3:2 grams/3 times per day) until symptom relief.

Results: Incubated at 35°C for 48 hours, the monocyte counts (MCs) of blended (3in1) revealed a safety level of less than 2.4x105 Cfu/g. Vitamins C, A, B1, and B3, which represented approximately 281±3.01, 201±1.53, 3.02±0.023, and 2±0.006 mg/100g DW, respectively, dominated the vitamin concentration of blended (3in1) significantly (p≤0.05) higher than all samples of vitamin content in this study. In terms of prebiotic activity, SCFA, such as acetate, butyrate, and propionate, AGs (PMC) produced (7% SCFA after 48 hours of incubation) significantly (p ≤ 0.05) less than AGs (PTC) (50% SCFA after 24 hours of incubation). Finally, based on biplot results, twenty-six (86%) out of the 30 patients improved dramatically over the three days in their clinical conditions on the symptoms, which involved cough, fatigue, and fever; therefore, they regained their abilities to smell and taste and the disappearance of the skin rashes.

Conclusion: Finally, the blended (3 in 1) MNVs have shown potent evidence of their use in traditional medicine and in preventing and combating COVID-19 symptoms among patients and contact persons. This suggests the potential use of AGs blended with ADLPs as natural antiviral agents to support the system.

Keywords: Gum arabic; Short-chain fatty acids; Vitamins; Prebiotic; Artificial stomach, High-Performance Liquid Chromatography (HPLC).

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Citation

Citation: Ahmed A. M. Elnour., et al. “Boosting Immunity to Compat Covid-19 Virus: A Prospective of Bioplot Validation Study Using Acacia Gums and Adansonia digitata Pulp". Acta Scientific Nutritional Health 6.6 (2022): 14-35.

Copyright

Copyright: © 2022 Ahmed A. M. Elnour., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.316

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